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Hackworth, Steven A (2005) PROOF OF CONCEPT DESIGN FOR A REMOTELY POWERED DEEP BRAIN STIMULATION DEVICE. Master's Thesis, University of Pittsburgh. (Unpublished)

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Parkinson's disease is a neurodegenerative disorder that causes tremor, stiffness, and slowness of movement. The first line of treatment for the disease is the administration of drugs. Over a period of time, these drugs slowly lose their affect to arrest the symptoms associated with Parkinson's disease. Once a patient becomes refractory to drug treatment, one alternative treatment option is Deep Brain Stimulation (DBS). In DBS, a probe is implanted in the basal ganglia area of the brain to administer electric pulses that curb the aforementioned symptoms. Although not fully understood, DBS is becoming a more widely accepted treatment, with various implantable devices currently on the market. These devices, however, require the implantation of a relatively large battery and control pack in the chest with subcutaneous wires threaded up through the neck to the top of the skull. The control pack and wires are a common source of irritation and infection, sometimes necessitating long periods of antibiotics or even removal of the device. Furthermore, the device is susceptible to magnetic interference and has a limited battery life. After the average 3- to 5-year lifespan of an implant's battery, another surgery is required to replace the device. The aim of this research is to design a small remotely powered device capable of driving a DBS probe from directly under the scalp. Successful development and proof of viability will form a basis for the conceptual redesign of currently marketed devices in order to eliminate the intrusive battery pack and wires, as well as the health risks commonly associated with them and the implantation procedure.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Hackworth, Steven Asah24@pitt.eduSAH24
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairMickle, Marlin Hmickle@ee.pitt.eduMICKLE
Committee CoChairLovell, Michael Rmlovell@pitt.eduMLOVELL
Committee MemberCain, James Tcain@ee.pitt.eduJTC
Committee MemberSun, Minguimrsun@neuronet.pitt.eduDRSUN
Committee MemberSclabassi,
Date: 9 November 2005
Date Type: Completion
Defense Date: 25 July 2005
Approval Date: 9 November 2005
Submission Date: 11 July 2005
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Institution: University of Pittsburgh
Schools and Programs: Swanson School of Engineering > Electrical Engineering
Degree: MSEE - Master of Science in Electrical Engineering
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: deep brain stimulation; inductive coupling; medical implant; remote powering
Other ID:, etd-07112005-114055
Date Deposited: 10 Nov 2011 19:50
Last Modified: 19 Dec 2016 14:36


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