Pitt Logo LinkContact Us

Development of Newly Built Chirped-pulsed Fourier Transform Microwave (CP-FTMW) Spectrometer for Studying Biomolecules in the Gas Phase

Bird, Ryan George (2011) Development of Newly Built Chirped-pulsed Fourier Transform Microwave (CP-FTMW) Spectrometer for Studying Biomolecules in the Gas Phase. Doctoral Dissertation, University of Pittsburgh.

[img]
Preview
PDF - Primary Text
Download (3277Kb) | Preview

    Abstract

    Recent advances in the technology of oscilloscopes and digital waveform generators have made it possible to shorten collection times, increase scan bandwidths and improve the overall sensitivity of microwave spectroscopy. Thus, microwave spectroscopy has become a powerful tool for the determination of the structures of molecules. The Pate group, at the University of Virginia, has developed a new technique called chirped-pulse Fourier transform microwave (CP-FTMW) spectroscopy that has the ability to measure the broadband pure rotational spectra of large molecules. Working in collaboration with the Pate group, we have developed, at the University of Pittsburgh, a small version of the UVa spectrometer. This version of the CP-FTMW spectrometer uses a narrower bandwidth pulse, ~500 MHz, which makes it possible to record a spectrum using lower power amplifiers at significantly reduced cost. Using this new spectrometer the pure rotational spectra of N,N΄-dimethylaniline, 4,4'-dimethylaminobenzonitrile, o-toluidine, m-toluidine, 4-fluorobenzyl alcohol, valeric acid, and δ-valerolactam were collected and studied. From these spectra, their three-dimensional structure, bonding properties, and intermolecular interactions were determined.


    Share

    Citation/Export:
    Social Networking:

    Details

    Item Type: University of Pittsburgh ETD
    ETD Committee:
    ETD Committee TypeCommittee MemberEmail
    Committee ChairPratt, David W,PRATT@pitt.edu
    Committee MemberWeber, Stephen G.sweber@pitt.edu
    Committee MemberSaxena, Sunil K.sksaxena@pitt.edu
    Committee MemberSears, Trevor J.sears@bnl.gov
    Title: Development of Newly Built Chirped-pulsed Fourier Transform Microwave (CP-FTMW) Spectrometer for Studying Biomolecules in the Gas Phase
    Status: Unpublished
    Abstract: Recent advances in the technology of oscilloscopes and digital waveform generators have made it possible to shorten collection times, increase scan bandwidths and improve the overall sensitivity of microwave spectroscopy. Thus, microwave spectroscopy has become a powerful tool for the determination of the structures of molecules. The Pate group, at the University of Virginia, has developed a new technique called chirped-pulse Fourier transform microwave (CP-FTMW) spectroscopy that has the ability to measure the broadband pure rotational spectra of large molecules. Working in collaboration with the Pate group, we have developed, at the University of Pittsburgh, a small version of the UVa spectrometer. This version of the CP-FTMW spectrometer uses a narrower bandwidth pulse, ~500 MHz, which makes it possible to record a spectrum using lower power amplifiers at significantly reduced cost. Using this new spectrometer the pure rotational spectra of N,N΄-dimethylaniline, 4,4'-dimethylaminobenzonitrile, o-toluidine, m-toluidine, 4-fluorobenzyl alcohol, valeric acid, and δ-valerolactam were collected and studied. From these spectra, their three-dimensional structure, bonding properties, and intermolecular interactions were determined.
    Date: 16 September 2011
    Date Type: Completion
    Defense Date: 27 July 2010
    Approval Date: 16 September 2011
    Submission Date: 13 July 2011
    Access Restriction: No restriction; Release the ETD for access worldwide immediately.
    Patent pending: No
    Institution: University of Pittsburgh
    Thesis Type: Doctoral Dissertation
    Refereed: Yes
    Degree: PhD - Doctor of Philosophy
    URN: etd-07132011-204049
    Uncontrolled Keywords: δ-valerolactam; 4-fluorobenzyl alcohol; 44’-dimethylaminobenzonitrile; internal rotor; NN΄-dimethylaniline; nuclear quadrupole; Chirped-pulsed Fourier Transform Microwave; m-toluidine; o-toluidine; valeric acid; 5-aminovaleric acid
    Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
    Date Deposited: 10 Nov 2011 14:51
    Last Modified: 10 Feb 2012 11:03
    Other ID: http://etd.library.pitt.edu/ETD/available/etd-07132011-204049/, etd-07132011-204049

    Actions (login required)

    View Item

    Document Downloads