Link to the University of Pittsburgh Homepage
Link to the University Library System Homepage Link to the Contact Us Form

Left Posterior Parietal Cortex Participates in Both Task Preparation and Episodic Retrieval

Phillips, Jeffrey Scott (2009) Left Posterior Parietal Cortex Participates in Both Task Preparation and Episodic Retrieval. Master's Thesis, University of Pittsburgh. (Unpublished)

Primary Text

Download (1MB) | Preview


Optimal memory retrieval depends not only on the fidelity of stored information, but also on the attentional state of the subject. Factors such as mental preparedness to engage in stimulus processing can facilitate or hinder memory retrieval. The current study used functional magnetic resonance imaging (fMRI) to distinguish preparatory brain activity before episodic and semantic retrieval tasks from activity associated with retrieval itself. The use of a catch-trial imaging paradigm permitted separation of neural responses to preparatory task cues and memory probes. Episodic and semantic task preparation engaged a common network, including the bilateral intraparietal sulcus (IPS), left fusiform gyrus (FFG), and pre-SMA. In the subsequent retrieval phase, the left IPS participated in a frontoparietal network which responded differentially to old and new stimuli. In contrast, the right IPS was influenced only by preparatory cues, with minimal modulation during memory retrieval. Preparatory activity in the left IPS and its sensitivity to old/new differences indicate that this brain region participates both in task preparation and in episodic retrieval. This dual response profile suggests the left IPS as a possible interface between systems for domain-general attentional control and episodic retrieval.


Social Networking:
Share |


Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Phillips, Jeffrey Scottjeffreyp@pitt.eduJEFFREYP
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairFiez, Julie Afiez@pitt.eduFIEZ
Committee MemberWolk, David
Committee MemberWheeler, Mark
Date: 5 June 2009
Date Type: Completion
Defense Date: 10 July 2008
Approval Date: 5 June 2009
Submission Date: 8 August 2008
Access Restriction: 5 year -- Restrict access to University of Pittsburgh for a period of 5 years.
Institution: University of Pittsburgh
Schools and Programs: Dietrich School of Arts and Sciences > Psychology
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: cognitive psychology; episodic memory; fMRI; functional magnetic resonance imaging; memory retrieval; retrieval mode
Other ID:, etd-08082008-104443
Date Deposited: 10 Nov 2011 19:58
Last Modified: 15 Nov 2016 13:48


Monthly Views for the past 3 years

Plum Analytics

Actions (login required)

View Item View Item