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The short-term effect of a balanced defecit diet on resting energy expenditure in overweight and obese males and females.

Kowallis, Ruth Ann (2007) The short-term effect of a balanced defecit diet on resting energy expenditure in overweight and obese males and females. Doctoral Dissertation, University of Pittsburgh. (Unpublished)

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There is variability in the pattern of weight change in response to a weight loss intervention (i.e., slowing of subsequent weight loss, cessation of weight loss, weight regain). A reduction in resting energy expenditure (REE) may partially explain the observed variability. Few studies have examined the effect of initial weight loss on change in REE. PURPOSE: To examine the change in REE in response to weight loss across a 4-week period in overweight and obese males and females. METHODS: Thirty-seven subjects (body mass index 25.0-39.9 kg/m2; males = 14, females = 23) participated in a 4-week intervention with random assignment to an Experimental Group or a no treatment Control Group. The experimental group was instructed to reduce energy intake to 1200-1500 kcal/d and participate in 100 min/wk of moderate aerobic exercise. The control group was instructed to maintain current eating and exercise behaviors. Assessments of body weight, body composition, and REE were conducted at 0 and 4 weeks. REE was expressed as absolute REE (kcal/d), REE relative to body weight, (kcal/kg/d), REE relative to lean body mass (kcal/kgLBM/d). RESULTS: Thirty-five subjects completed the study (94.6%). There were significant differences (p<0.05) for change in outcomes between the experimental and control groups for body weight (-3.3+1.7 vs. 0.6+1.1 kg) lean body mass (-0.6+0.9 vs. 0.2+0.9 kg), absolute REE (-205.8+193.0 vs. -11.4+ 140.6 kcal/d), and REE relative to lean body mass (-3.3+2.9 vs. -0.4+2.6 kcal/kgLBM/d). There was a trend toward a significant difference between the groups (p = .07) for REE relative to body weight (-1.4+1.9 vs. -0.3+1.5 kcal/kg/d). When the groups were combined, there was a correlation between change in REE and change in body weight was r=0.41 (p<.05), and change in REE and change in lean body mass was r=0.44 (p<.01). CONCLUSIONS: Results indicate that absolute and relative REE are significantly reduced in response to weight loss over a 4-week period. The modest correlations between change in REE and both body weight and lean body mass may suggest that additional physiological mechanisms influence REE during the acute phase of weight loss.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Kowallis, Ruth
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairJakicic, John Mjjakicic@pitt.eduJJAKICIC
Committee MemberOtto, Amy Dayotto@pitt.eduAYOTTO
Committee MemberRubinstein, Elaine Nenr@pitt.eduENR
Committee MemberNagle, Elizabeth Fnagle@pitt.eduNAGLE
Committee MemberGoss, Fredric Lgoss@pitt.eduGOSS
Date: 29 January 2007
Date Type: Completion
Defense Date: 24 August 2006
Approval Date: 29 January 2007
Submission Date: 20 October 2006
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Institution: University of Pittsburgh
Schools and Programs: School of Education > Health, Physical, Recreational Education
Degree: PhD - Doctor of Philosophy
Thesis Type: Doctoral Dissertation
Refereed: Yes
Uncontrolled Keywords: diet; metabolic rate; resting energy expenditure; weight loss
Other ID:, etd-10202006-151514
Date Deposited: 10 Nov 2011 20:03
Last Modified: 15 Nov 2016 13:50


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