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PUTTING CRAVING INTO CONTEXT: EFFECTS OF PERCEIVED SMOKING OPPORTUNITY ON THE NEURAL RESPONSE TO CIGARETTE CUE EXPOSURE

Wilson, Stephen Jeffrey (2005) PUTTING CRAVING INTO CONTEXT: EFFECTS OF PERCEIVED SMOKING OPPORTUNITY ON THE NEURAL RESPONSE TO CIGARETTE CUE EXPOSURE. Master's Thesis, University of Pittsburgh. (Unpublished)

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Abstract

Recent years have seen the emergence of research applying functional neuroimaging to the study of cue-elicited drug craving. This research has begun to identify a distributed system of brain activity during drug craving. Functional magnetic resonance imaging (fMRI) was used to examine the effects of smoking expectancy on the neural response to neutral (e.g., roll of tape) and smoking-related (holding a cigarette) stimuli in male cigarette smokers deprived of nicotine for 8 hours. As predicted, several brain regions exhibited differential activation during cigarette versus neutral cue exposure. Moreover, instructions about smoking opportunity affected cue-elicited activation in several regions. These results highlight the importance of perceived drug availability in the neurobiological response to drug cues.

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Details

Item Type: University of Pittsburgh ETD
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Wilson, Stephen Jeffreysjwilson@pitt.eduSJWILSON
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairSayette, Michaelsayette@pitt.eduSAYETTE
Committee MemberReichle, Erikreichle@pitt.eduREICHLE
Committee MemberFiez, Juliefiez@pitt.eduFIEZ
Date: 3 February 2005
Date Type: Completion
Defense Date: 22 June 2004
Approval Date: 3 February 2005
Submission Date: 10 November 2004
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Institution: University of Pittsburgh
Schools and Programs: Dietrich School of Arts and Sciences > Psychology
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: cue reactivity; drug craving; prefrontal cortex; drug cue; neuroimaging
Other ID: http://etd.library.pitt.edu/ETD/available/etd-11102004-104431/, etd-11102004-104431
Date Deposited: 10 Nov 2011 20:04
Last Modified: 15 Nov 2016 13:51
URI: http://d-scholarship.pitt.edu/id/eprint/9615

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