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NICOTINE DEPENDENCE AND LABORATORY CUE-INDUCED CIGARETTE CRAVING

DUNBAR, MICHAEL (2012) NICOTINE DEPENDENCE AND LABORATORY CUE-INDUCED CIGARETTE CRAVING. Master's Thesis, University of Pittsburgh. (Unpublished)

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Abstract

NICOTINE DEPENDENCE AND LABORATORY CUE-INDUCED CIGARETTE CRAVING
Michael Dunbar, M.S.
University of Pittsburgh, 2011

Background: The relationship between laboratory cue-induced craving and nicotine dependence is unclear. Some models consider cue-induced craving part of dependence, while others imply that responsiveness to cues disappears with dependence. These relationships are further complicated by different measures of nicotine dependence and craving. Method: Participants (n=207, 57% men) were daily smokers averaging 15.92 (6.70) cigarettes per day. We examined data from 4 cue-reactivity sessions, with cue sets (smoking, negative affect, positive affect, neutral) counterbalanced across sessions. In each session, after a 30-minute deprivation period, participants viewed 30 cue-relevant photos validated for content and shown over 3 minutes (6 seconds each). Participants rated their craving before and after cues (QSU-Brief, scaled as 1-49). Participants completed measures of nicotine dependence (FTND, NDSS, WISDM-68), which were used to predict craving. Multiple regression models were used to predict cue-induced craving (pre-post cue change scores) for QSU Factors 1 and 2. Results: Dependence measures were associated with background craving across sessions, but did not predict cue change in craving (Factor 1 or 2) for any cue. Conclusion: Laboratory cue-induced craving in response to smoking-relevant cues is unrelated to nicotine dependence, as traditionally assessed. Future work should investigate the relationship between reactivity to cues and actual smoking behavior, in order to better understand how reactivity to cues and dependence may function independently or synergistically to influence smoking behavior.


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Details

Item Type: University of Pittsburgh ETD
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
DUNBAR, MICHAELMSD13@PITT.EDUMSD13
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairSHIFFMAN, SAULSHIFFMAN@PINNEYASSOCIATES.COM
Committee MemberSAYETTE, MICHAELSAYETTE@PITT.EDUSAYETTE
Committee MemberPERKINS, KENNETHPERKINSKA@UPMC.EDUKPERKINS
Date: 26 January 2012
Date Type: Publication
Defense Date: 28 January 2011
Approval Date: 26 January 2012
Submission Date: 15 December 2011
Access Restriction: 5 year -- Restrict access to University of Pittsburgh for a period of 5 years.
Number of Pages: 72
Institution: University of Pittsburgh
Schools and Programs: Dietrich School of Arts and Sciences > Psychology
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: CUES, SMOKING, NICOTINE DEPENDENCE
Date Deposited: 26 Jan 2012 21:28
Last Modified: 26 Jan 2017 06:15
URI: http://d-scholarship.pitt.edu/id/eprint/10808

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