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Characterization of anterior cerebral artery blood flow in resting state by using transcranial Doppler

Huang, Hanrui (2013) Characterization of anterior cerebral artery blood flow in resting state by using transcranial Doppler. Master's Thesis, University of Pittsburgh. (Unpublished)

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Abstract

Transcranial Doppler (TCD) recordings are used to monitor cerebral blood flow in main cerebral arteries. The resting state is usually characterized by using the mean velocity or the maximum Doppler shift frequency (an envelope signal) by insonating the middle cerebral arteries (MCAs). In this study, we characterized the cerebral blood flow in the anterior cerebral arteries (ACAs). We analyzed both the envelope signals and the raw signals obtained from bilateral insonation. We recruited 20 healthy subjects and conducted the data acquisition for 15 minutes. Features were extracted from the time domain, the frequency domain and the time-frequency domain. The results showed that gender-based statistical difference exists in the frequency domain and the time-frequency domain. However, no handedness effect was found. In the time domain, the information-theoretic features showed that the mutual dependence is higher in raw signals than in envelope signals. Finally, we concluded that insonating the ACA will serve as a complement of the MCA studies. Additionally, the investigation of the raw signals provided us with additional information that is not otherwise available from the envelope signals. The direct TCD raw-data utilization is therefore validated as a valuable resting-state characterization method.


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Details

Item Type: University of Pittsburgh ETD
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Huang, Hanruihah45@pitt.eduHAH45
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairSejdić, Ervinesejdic@pitt.eduESEJDIC
Committee MemberMao, Zhi-Hongzhm4@pitt.eduZHM4
Committee MemberChaparro, Luis F.lfch@pitt.edu LFCH
Date: 27 June 2013
Date Type: Publication
Defense Date: 25 March 2013
Approval Date: 27 June 2013
Submission Date: 26 March 2013
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 58
Institution: University of Pittsburgh
Schools and Programs: Swanson School of Engineering > Electrical Engineering
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: Transcrannial Doppler, anterior cerebral artery, resting-state characteristics
Date Deposited: 27 Jun 2013 14:53
Last Modified: 15 Nov 2016 14:10
URI: http://d-scholarship.pitt.edu/id/eprint/17932

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  • Characterization of anterior cerebral artery blood flow in resting state by using transcranial Doppler. (deposited 27 Jun 2013 14:53) [Currently Displayed]

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