Bleton, Heloise
(2014)
Cognitive Function Evaluation Following a Cervical Spinal Cord Injury: A Case Study through the Middle Cerebral Arteries Using Transcranial Doppler.
Master's Thesis, University of Pittsburgh.
(Unpublished)
This is the latest version of this item.
Abstract
Spinal cord injury (SCI) is one of the most common neurological disorders. In this paper, we examined the consequences of upper SCI in a male participant on cerebral blood flow velocity (CBFV). In particular, transcranial Doppler (TCD) was used to study these effects through middle cerebral arteries (MCA) during resting-state periods and during cognitive challenges (non-verbal word-generation tasks and geometric-rotation tasks). Signal characteristics were analyzed from raw signals and envelope signals (maximum velocity) in time domain, frequency domain and time frequency domain. Frequency features pointed out an increase of peak frequency in L-MCA and R-MCA raw signals which revealed stronger cerebral blood flow during geometric/verbal processes respectively. This underlined a slight dominance of the right hemisphere during word-generation periods and a slight dominance of the left
hemisphere during geometric processes. This finding was confirmed by cross-correlation in time domain and by entropy rate in information-theoretic domain. Comparing our results to other neurological disorders (Alzheimer’s disease, Parkinson’s disease, autism, epilepsy, traumatic brain injury) showed that the SCI had similar effects such as a general decreased cerebral blood flow and similar regular hemispheric dominance in a few cases.
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Details
| Item Type: |
University of Pittsburgh ETD
|
| Status: |
Unpublished |
| Creators/Authors: |
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| ETD Committee: |
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| Date: |
19 September 2014 |
| Date Type: |
Publication |
| Defense Date: |
8 July 2014 |
| Approval Date: |
19 September 2014 |
| Submission Date: |
9 July 2014 |
| Access Restriction: |
3 year -- Restrict access to University of Pittsburgh for a period of 3 years. |
| Number of Pages: |
73 |
| Institution: |
University of Pittsburgh |
| Schools and Programs: |
Swanson School of Engineering > Electrical Engineering |
| Degree: |
MSEE - Master of Science in Electrical Engineering |
| Thesis Type: |
Master's Thesis |
| Refereed: |
Yes |
| Uncontrolled Keywords: |
transcranial Doppler, spinal cord injury, cognitive tasks, cerebral blood flow
velocity. |
| Date Deposited: |
19 Sep 2014 16:46 |
| Last Modified: |
19 Sep 2017 05:15 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/22305 |
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Cognitive Function Evaluation Following a Cervical Spinal Cord Injury: A Case Study through the Middle Cerebral Arteries Using Transcranial Doppler. (deposited 19 Sep 2014 16:46)
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