Feature tracking measurement of dyssynchrony from cardiovascular magnetic resonance cine acquisitions: Comparison with echocardiographic speckle tracking

Onishi, T and Saha, SK and Ludwig, DR and Onishi, T and Marek, JJ and Cavalcante, JL and Schelbert, EB and Schwartzman, D and Gorcsan, J (2013) Feature tracking measurement of dyssynchrony from cardiovascular magnetic resonance cine acquisitions: Comparison with echocardiographic speckle tracking. Journal of Cardiovascular Magnetic Resonance, 15 (1). ISSN 1097-6647

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Abstract

Background: Analysis of left ventricular (LV) mechanical dyssynchrony may provide incremental prognostic information regarding cardiac resynchronization therapy (CRT) response in addition to QRS width alone. Our objective was to quantify LV dyssynchrony using feature tracking post processing of routine cardiovascular magnetic resonance (CMR) cine acquisitions (FT-CMR) in comparison to speckle tracking echocardiography. Methods. We studied 72 consecutive patients who had both steady-state free precession CMR and echocardiography. Mid-LV short axis CMR cines were analyzed using FT-CMR software and compared with echocardiographic speckle tracking radial dyssynchrony (time difference between the anteroseptal and posterior wall peak strain). Results: Radial dyssynchrony analysis was possible by FT-CMR in all patients, and in 67 (93%) by echocardiography. Dyssynchrony by FT-CMR and speckle tracking showed limits of agreement of strain delays of ± 84 ms. These were large (up to 100% or more) relative to the small mean delays measured in more synchronous patients, but acceptable (mainly <25%) in those with mean delays of >200 ms. Radial dyssynchrony was significantly greater in wide QRS patients than narrow QRS patients by both FT-CMR (radial strain delay 230 ± 94 vs. 77 ± 92* ms) and speckle tracking (radial strain delay 242 ± 101 vs. 75 ± 88* ms, all *p < 0.001). Conclusions: FT-CMR delivered measurements of radial dyssynchrony from CMR cine acquisitions which, at least for the patients with more marked dyssynchrony, showed reasonable agreement with those from speckle tracking echocardiography. The clinical usefulness of the method, for example in predicting prognosis in CRT patients, remains to be investigated. © 2013 Onishi et al.; licensee BioMed Central Ltd.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Onishi, T Saha, SK Ludwig, DR Onishi, T Marek, JJ Cavalcante, JL jlc209@pitt.edu JLC209 0000-0002-3632-2074 Schelbert, EB ers77@pitt.edu ERS77 Schwartzman, D Gorcsan, J gorcsan@pitt.edu GORCSAN
Date:	21 October 2013
Date Type:	Publication
Journal or Publication Title:	Journal of Cardiovascular Magnetic Resonance
Volume:	15
Number:	1
DOI or Unique Handle:	10.1186/1532-429x-15-95
Schools and Programs:	School of Medicine > Medicine
Refereed:	Yes
ISSN:	1097-6647
Date Deposited:	02 Dec 2016 16:09
Last Modified:	02 Feb 2019 16:58
URI:	http://d-scholarship.pitt.edu/id/eprint/29666

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