PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis

Tauzin, M and Rabalais, A and Hagan, JL and Wood, CG and Ferris, RL and Walvekar, RR (2010) PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis. World Journal of Surgical Oncology, 8.

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Abstract

Objective: To study the retropharyngeal lymph node status (RPLN) by pretreatment PET-CT imaging in patients with squamous cell carcinomas of the oropharynx (OPSCC). Study Design: Retrospective.Methods: 101 patients with a biopsy proven OPSCC were identified. 53 patients meeting inclusion criteria were further analyzed.Results: The frequency of RPLN was 20.8% (11/53). Advanced T stage cancer (OR = 5.6250, 95% CI: 1.06 - 29.80, p = 0.0410) and advanced clinical N stage cancer (i.e. N2+) had higher odds (OR = 3.9773, 95% CI: 0.9628 - 16.4291) of being RPLN positive as compared to N0-1 patients.Conclusions: Pre-treatment PET-CT can be used as a staging tool to aid in treatment planning of OPSCC, as rates of RPLN and nodal metastasis are consistent with those reported in the literature. Advanced T and N stage are associated with a greater odds ratio of being RPLN positive by PET-CT imaging. © 2010 Tauzin et al; licensee BioMed Central Ltd.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Tauzin, M Rabalais, A Hagan, JL Wood, CG Ferris, RL rlf1@pitt.edu RLF1 Walvekar, RR
Date:	16 August 2010
Date Type:	Publication
Journal or Publication Title:	World Journal of Surgical Oncology
Volume:	8
DOI or Unique Handle:	10.1186/1477-7819-8-70
Schools and Programs:	School of Medicine > Otolaryngology School of Medicine > Surgery
Refereed:	Yes
Date Deposited:	14 Nov 2016 17:39
Last Modified:	04 Feb 2019 15:58
URI:	http://d-scholarship.pitt.edu/id/eprint/30245

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