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Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region

Byrwa-Hill, Brandy M. and Venkat, Arvind and Presto, Albert A. and Rager, Judith R. and Gentile, Deborah and Talbott, Evelyn (2020) Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region. International Journal of Environmental Research and Public Health, 17 (22). p. 8619. ISSN 1660-4601

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Abstract

Asthma affects millions of people globally and is especially concerning in populations living with poor air quality. This study examines the association of ambient outdoor air pollutants on asthma-related emergency department (ED) visits in children and adults throughout the Pittsburgh region. A time-stratified case-crossover design is used to analyze the lagged effects of fine particulate matter (PM2.5) and gaseous pollutants, e.g., ozone (O3), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) on asthma-related ED visits (n = 6682). Single-, double-, and multi-pollutant models are adjusted for temperature and analyzed using conditional logistic regression. In children, all models show an association between O3 and increased ED visits at lag day 1 (OR: 1.12, 95% CI, 1.03–1.22, p < 0.05) for the double-pollutant model (OR: 1.10, 95% CI: 1.01-1.20, p < 0.01). In adults, the single-pollutant model shows associations between CO and increased ED visits at lag day 5 (OR: 1.13, 95% CI, 1.00–1.28, p < 0.05) and average lag days 0–5 (OR: 1.22, 95% CI: 1.00–1.49, p < 0.05), and for NO2 at lag day 5 (OR: 1.04, 95% CI: 1.00–1.07, p < 0.05). These results show an association between air pollution and asthma morbidity in the Pittsburgh region and underscore the need for mitigation efforts to improve public health outcomes.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Byrwa-Hill, Brandy M.
Venkat, Arvind
Presto, Albert A.
Rager, Judith R.
Gentile, Deborah
Talbott, Evelyneot1@pitt.edu
Date: 20 November 2020
Date Type: Publication
Journal or Publication Title: International Journal of Environmental Research and Public Health
Volume: 17
Number: 22
Publisher: MDPI AG
Page Range: p. 8619
DOI or Unique Handle: 10.3390/ijerph17228619
Schools and Programs: School of Public Health > Environmental and Occupational Health
Refereed: Yes
Uncontrolled Keywords: asthma, pollution, emergency department visits, pediatrics, adults, ozone
ISSN: 1660-4601
Official URL: http://dx.doi.org/10.3390/ijerph17228619
Funders: The Heinz Endowments
Article Type: Research Article
Date Deposited: 27 Jun 2022 18:17
Last Modified: 27 Jun 2022 18:17
URI: http://d-scholarship.pitt.edu/id/eprint/43112

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