Kahn, D and Esquivel, CO and Makowka, L and Madrigal-Torres, M and Yunis, E and Iwatsuki, S and Starzl, TE
(1989)
Causes of death after liver transplantation in children treated with cyclosporine and steroids.
Clinical Transplantation, 3 (3).
150 - 155.
ISSN 0902-0063
Abstract
Two-hundred-and-twenty-seven children underwent orthotopic liver transplantation between March 1980 and March 1986. Seventy (31%) patients died during the study period. Four patients who died within 24 hours of the initial liver transplant and 5 patients who died outside of our institution were excluded from the analysis. Liver failure, related to either thrombosis of the hepatic artery, primary non-function of the graft or rejection accounted for 25 of the remaining 61 deaths. In 21 patients death was related to overwheming sepsis while 7 patients died from excessive bleeding. Eight of the deaths were due to a miscellaneous group of causes. Twenty percent of the 150 patients who received a single liver transplant died compared to a death rate of 50% in patients who underwent three transplants. Eighty-five percent of the deaths occurred within 6 months after the initial liver transplant. Liver failure was the cause in the majority of the early deaths whereas the later deaths were more likely to be due to sepsis. This detailed analysis of the causes of death after pediatric liver transplantation in a large group of patients has revealed that advances in certain areas could lead to even better results.
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| Item Type: |
Article
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| Status: |
Published |
| Creators/Authors: |
| Creators | Email | Pitt Username | ORCID  |
|---|
| Kahn, D | | | | | Esquivel, CO | | | | | Makowka, L | | | | | Madrigal-Torres, M | | | | | Yunis, E | | | | | Iwatsuki, S | | | | | Starzl, TE | tes11@pitt.edu | TES11 | |
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| Centers: |
Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute |
| Date: |
1 January 1989 |
| Date Type: |
Publication |
| Journal or Publication Title: |
Clinical Transplantation |
| Volume: |
3 |
| Number: |
3 |
| Page Range: |
150 - 155 |
| Institution: |
University of Pittsburgh |
| Refereed: |
Yes |
| ISSN: |
0902-0063 |
| Other ID: |
uls-drl:31735062110279, Starzl CV No. 986 |
| Date Deposited: |
08 Apr 2010 17:16 |
| Last Modified: |
02 Feb 2019 13:56 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/4372 |
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