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Liver failure occurring as a component of exertional heatstroke.

Hassanein, T and Perper, JA and Tepperman, L and Starzl, TE and Van Thiel, DH (1991) Liver failure occurring as a component of exertional heatstroke. Gastroenterology, 100 (5 Pt 1). 1442 - 1447. ISSN 0016-5085

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Abstract

An unusual case of an exertional heatstroke in a healthy 25-year-old man is presented. Initially, the patient was deeply comatose and developed severe rhabdomyolysis and massive hepatic necrosis. Subsequently, he received a liver transplant with remarkable improvement in his mental status, although the rhabdomyolysis continued. The patient died 41 days after the transplant due to a complicating infection. Providing that infections can be effectively controlled, liver transplants might be a promising therapeutic alternative for the few patients who survive the initial neurological consequences of this unusual event.

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Hassanein, T
Perper, JA
Tepperman, L
Starzl, TEtes11@pitt.eduTES11
Van Thiel, DH
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: May 1991
Date Type: Publication
Journal or Publication Title: Gastroenterology
Volume: 100
Number: 5 Pt 1
Page Range: 1442 - 1447
Institution: University of Pittsburgh
Refereed: Yes
Uncontrolled Keywords: Adult, Heat Exhaustion, Hepatic Encephalopathy, Humans, Liver, Liver Transplantation, Male, Muscles, Physical Exertion, Rhabdomyolysis, Sepsis
ISSN: 0016-5085
Funders: NIDDK NIH HHS (R01 DK029961-19)
Other ID: uls-drl:31735062117787, Starzl CV No. 1227
Date Deposited: 08 Apr 2010 17:21
Last Modified: 05 Dec 2017 16:59
URI: http://d-scholarship.pitt.edu/id/eprint/4613

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