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Adult respiratory distress syndrome secondary to end-stage liver disease—successful outcome following liver transplantation

Doyle, HR and Marino, IR and Miro, A and Scott, V and Martin, M and Fung, J and Kramer, D and Starzl, TE (1993) Adult respiratory distress syndrome secondary to end-stage liver disease—successful outcome following liver transplantation. Transplantation, 55 (2). 292 - 296. ISSN 0041-1337

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Abstract

The adult respiratory distress syndrome (ARDS) com­plicating liver failure carries a 100% mortality. Two cases of ARDS that resolved following liver transplantation have been reported, one associated with acute allograft rejection, and the second due to sepsis. There is, however, a great reluctance to transplant these very-high-risk patients. We report the first series of patients with ARDS secondary to liver failure who successfully underwent OLTX. No patient had sepsis or pneumonia. Posttransplant mechanical ventilation was required for a median of 14 days (range 6-37 days). All patients in this series are alive and well, with a follow-up of 6-15 months. This demonstrates that ARDS associated with liver failure, an otherwise uniformly lethal complica­tion, can respond dramatically to OLTX. © 1993 by William & Wilkins.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Doyle, HR
Marino, IR
Miro, A
Scott, V
Martin, M
Fung, J
Kramer, D
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1993
Date Type: Publication
Journal or Publication Title: Transplantation
Volume: 55
Number: 2
Page Range: 292 - 296
DOI or Unique Handle: 10.1097/00007890-199302000-00012
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0041-1337
Other ID: uls-drl:31735062113372, Starzl CV No. 1550
Date Deposited: 08 Apr 2010 17:26
Last Modified: 02 Feb 2019 13:57
URI: http://d-scholarship.pitt.edu/id/eprint/4936

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