Browse by Publication

Retseck, J and VanderWeele, R and Lin, HM and Lin, Y and Butterfield, LH and Tarhini, AA (2016) Phenotypic and functional testing of circulating regulatory T cells in advanced melanoma patients treated with neoadjuvant ipilimumab. Journal for ImmunoTherapy of Cancer, 4 (1).

Kaufman, HL and Butterfield, LH and Coulie, PG and Demaria, S and Ferris, RL and Galon, J and Khleif, SN and Mellman, I and Ohashi, PS and Overwijk, WW and Topalian, SL and Marincola, FM (2016) Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule. Journal for ImmunoTherapy of Cancer, 4 (1).

Radomski, M and Zeh, HJ and Edington, HD and Pingpank, JF and Butterfield, LH and Whiteside, TL and Wieckowski, E and Bartlett, DL and Kalinski, P (2016) Prolonged intralymphatic delivery of dendritic cells through implantable lymphatic ports in patients with advanced cancer. Journal for ImmunoTherapy of Cancer, 4 (1).

Yuan, J and Hegde, PS and Clynes, R and Foukas, PG and Harari, A and Kleen, TO and Kvistborg, P and Maccalli, C and Maecker, HT and Page, DB and Robins, H and Song, W and Stack, EC and Wang, E and Whiteside, TL and Zhao, Y and Zwierzina, H and Butterfield, LH and Fox, BA (2016) Novel technologies and emerging biomarkers for personalized cancer immunotherapy. Journal for ImmunoTherapy of Cancer, 4 (1).

Kansy, Benjamin A and Lin, Yan and Ding, Fei and Gibson, Sandra Poveda and Jie, Hyun-Bae and Ferris, Robert L (2015) Anti-EGFR mAb cetuximab therapy increases T cell receptor (TCR) diversity in the peripheral blood and focuses TCR richness in the tumor microenvironment. Journal for ImmunoTherapy of Cancer, 3 (S2).

Trivedi, Sumita and Srivastava, Raghvendra M and Concha-Benavente, Fernando and Garcia-Bates, Tatiana M and Li, Jing and Ferris, Robert L (2015) Anti-EGFR targeted monoclonal antibody isotype influences anti-tumor immunity in head and neck cancer patients. Journal for ImmunoTherapy of Cancer, 3 (S2).

Srivastava, Raghvendra M and Clump, David A and Ferris, Robert L (2015) Anti-PD-1 mAb pre-radiotherapy (RT) loading dose and fractionated RT induce better tumor-specific immunity and tumor shrinkage than sequential administration in an HPV+ head and neck cancer model. Journal for ImmunoTherapy of Cancer, 3 (S2).

Bruno, Tullia and Ebner, Peggy and Moore, Brandon and Munson, Daniel and Mitchell, John and Kern, Jeffrey and Vignali, Dario AA and Slansky, Jill (2015) Antigen presentation by tumor infiltrating B cells influences CD4 T cell phenotype and function in primary lung cancer patient tumors. Journal for ImmunoTherapy of Cancer, 3 (S2).

Du, Samuel and Santos, Patricia M and Tawbi, Hussein and Tarhini, Ahmad and Kirkwood, John M and Butterfield, Lisa H (2015) CD8+ T cell responses in metastatic melanoma patients receiving an adenovirally antigen engineered dendritic cell vaccine +/- IFN-α. Journal for ImmunoTherapy of Cancer, 3 (S2).

Liang, Xiaoyan and Wang, Wenqian and Li, Guanqiao and Zhang, Xiaokui and Jankovic, Vladimir and Herzberg, Uri and Hofgartner, Wolfgang and Lotze, Michael T (2015) Efficacy of adoptive transfer of expanded fetal liver-derived precursor syngeneic and allogeneic murine NK cells against solid tumors. Journal for ImmunoTherapy of Cancer, 3 (S2).

Overacre, Abigail E and Chikina, Maria and Delgoffe, Greg M and Vignali, Dario AA (2015) Elucidating the role of Neuropilin-1 in intra-tumoral regulatory T cell stability. Journal for ImmunoTherapy of Cancer, 3 (S2).

Kohanbash, Gary and Shrivastav, Shruti and Ahn, Brian and Hou, Yafei and Costello, Joseph and Okada, Hideho (2015) IDH mutation-induced suppression of type-1 anti-glioma immune response. Journal for ImmunoTherapy of Cancer, 3 (S2).

Fecek, Ronald J and Wang, Simeng and Storkus, Walter J (2015) Immunotherapeutic targeting of HSP90 client proteins in BRAF-inhibitor resistant melanoma. Journal for ImmunoTherapy of Cancer, 3 (S2).

Mehta, Kathan and Appleman, Leonard and Wang, Hong and Tarhini, Ahmad and Parikh, Rahul (2015) Impact of annual hospital volume of high dose interleukin-2 infusions on in-patient mortality in patients with melanoma and renal cell carcinoma. Journal for ImmunoTherapy of Cancer, 3 (S2).

Kansy, Benjamin A and Srivastava, Raghvendra M and Jie, Hyun-Bae and Shayan, Gulidanna and Lei, Yu and Li, Jing and Gooding, William and Brandau, Sven and Lang, Stephan and Schmitt, Nicole and Freeman, Gordon J and Clump, David A and Ferris, Robert L (2015) Level of PD-1 expression on CD8+ T cells influence prognosis and respond to PD-1 therapy in a murine model. Journal for ImmunoTherapy of Cancer, 3 (S2).

Sznol, Mario and Fishman, Mayer and Escudier, Bernard and McDermott, David F and Kluger, Harriet and Stadler, Walter M and Perez-Gracia, Jose and McNeel, Douglas G and Curti, Brendan D and Harrison, Michael R and Plimack, Elizabeth R and Appleman, Leonard and Fong, Lawrence and Drake, Charles G and Young, Tina C and Chasalow, Scott D and Ross-MacDonald, Petra and Simon, Jason S and Walker, Dana and Choueiri, Toni K (2015) Markers of inflammation are associated with clinical outcomes in patients with metastatic renal cell carcinoma treated with nivolumab. Journal for ImmunoTherapy of Cancer, 3 (S2).

Concha-Benavente, Fernando and Srivastava, Raghvendra M and Kansy, Benjamin and Ferris, Robert L (2015) PD-1 is a marker of activation on tumor infiltrating NK cells in head and neck cancer. Journal for ImmunoTherapy of Cancer, 3 (S2).

Long, Georgina V and Dummer, Reinhard and Ribas, Antoni and Puzanov, Igor and Michielin, Olivier and VanderWalde, Ari and Andtbacka, Robert HI and Cebon, Jonathan and Fernandez, Eugenio and Malvehy, Josep and Olszanski, Anthony J and Gajewski, Thomas F and Kirkwood, John M and Kuznetsova, Olga and Chen, Lisa and Kaufman, David R and Chou, Jeffrey and Hodi, F Stephen (2015) A Phase I/III, multicenter, open-label trial of talimogene laherparepvec (T-VEC) in combination with pembrolizumab for the treatment of unresected, stage IIIb-IV melanoma (MASTERKEY-265). Journal for ImmunoTherapy of Cancer, 3 (S2).

Ferris, Robert L and Even, Caroline and Haddad, Robert and Tahara, Makoto and Goswami, Trishna and Franks, April and Emeribe, Ugochi and Jarkowski, Anthony and Melillo, Giovanni and Licitra, Lisa (2015) Phase III, randomized, open-label study of durvalumab (MEDI4736) monotherapy, or durvalumab + tremelimumab, versus standard of care (SoC), in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): eagle. Journal for ImmunoTherapy of Cancer, 3 (S2).

Baar, Joseph and Storkus, Walter J and Finke, James and Butterfield, Lisa and Lazarus, Hillard and Reese, Jane and Downes, Katharine and Budd, Thomas and Brufsky, Adam and Fu, Pingfu (2015) Pilot trial of a type I - polarized autologous dendritic cell vaccine incorporating tumor blood vessel antigen-derived peptides in patients with metastatic breast cancer. Journal for ImmunoTherapy of Cancer, 3 (S1).

Hansen, Morten and Wieckowski, Eva and Svane, Inge Marie and Edwards, Robert P and Kalinski, Pawel (2015) Selective costimulation by IL-15R/IL-15, but not IL-2R/IL-2, allows the induction of high numbers of tumor-specific CD8+ T cells by human dendritic cells matured in conditions of acute inflammation. Journal for ImmunoTherapy of Cancer, 3 (S2).

Vujanovic, Lazar and Stahl, Elizabeth and Pardee, Angela and Watkins, Simon and Gibson, Gregory and Butterfield, Lisa H (2015) Tumor-derived alpha fetoprotein directly impacts human natural killer cell activity and viability. Journal for ImmunoTherapy of Cancer, 3 (S2).

Santos, Patricia M and Pardee, Angela and Delgoffe, Greg M and Butterfield, Lisa H (2015) Tumor-derived alpha-fetoprotein (tAFP) causes immune and metabolic dysfunction in monocyte-derived dendritic cells. Journal for ImmunoTherapy of Cancer, 3 (S2).

Andrews, Lawrence P and Szymczak-Workman, Andrea L and Workman, Creg J and Vignali, Dario AA (2015) The extent of metalloproteinase-mediated LAG3 cleavage limits the efficacy of PD1 blockade. Journal for ImmunoTherapy of Cancer, 3 (S2).

Li, J and Srivastava, RM and Ettyreddy, A and Ferris, RL (2015) Cetuximab ameliorates suppressive phenotypes of myeloid antigen presenting cells in head and neck cancer patients. Journal for ImmunoTherapy of Cancer, 3 (1).

Liu, Chang and Chikina, Maria D and Workman, Creg J and Vignali, Dario AA (2015) Remodulation of the tumor microenvironment by regulatory T cells. Journal for ImmunoTherapy of Cancer, 3 (P409). ISSN 2051-1426

Tarhini, AA and Zahoor, H and Lin, Y and Malhotra, U and Sander, C and Butterfield, LH and Kirkwood, JM (2015) Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma. Journal for ImmunoTherapy of Cancer, 3 (1).

Overacre, AE and Kurtulus, S and Sznol, M and Pardoll, DM and Anderson, A and Vignali, DAA (2015) Combination immunotherapy: Where do we go from here? Journal for ImmunoTherapy of Cancer, 3 (1).

Pardee, AD and Yano, H and Weinstein, AM and Ponce, AAK and Ethridge, AD and Normolle, DP and Vujanovic, L and Mizejewski, GJ and Watkins, SC and Butterfield, LH (2015) Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma. Journal for ImmunoTherapy of Cancer, 3 (1).

Muthuswamy, R and Wang, L and Pitteroff, J and Gingrich, JR and Kalinski, P (2015) Combination of IFNα and poly-I: C reprograms bladder cancer microenvironment for enhanced CTL attraction. Journal for ImmunoTherapy of Cancer, 3 (1).

Butterfield, LH and Disis, ML and Fox, BA and Khleif, SN and Marincola, FM (2015) Preamble to the 2015 SITC immunotherapy biomarkers taskforce. Journal for ImmunoTherapy of Cancer, 3 (1).

Boyiadzis, Michael and Hong, Chang-Sook and Whiteside, Theresa L (2015) Biologically-active exosomes in plasma of AML patients inhibit innate immunity and promote leukemia progression. Journal for ImmunoTherapy of Cancer, 3 (Suppl ). P278 - P278. ISSN 2051-1426

Boyiadzis, Michael and Hong, Chang-Sook and Whiteside, Theresa L (2015) Circulating exosomes carrying an immunosuppressive cargo may interfere with adoptive cell therapies in leukemia. Journal for ImmunoTherapy of Cancer, 3 (Suppl ). P60 - P60. ISSN 2051-1426

Downs-Canner, Stephanie and Ravindranathan, Roshni and Edwards, Robert P and Kalinski, Pawel and Odunsi, Kunle and Bartlett, David L and Obermajer, Natasa (2015) Ex-Th17 Foxp3+ T cells - a novel subset of Foxp3+ T cells induced in cancer. Journal for ImmunoTherapy of Cancer, 3 (Suppl ). P273 - P273. ISSN 2051-1426

Gupta, Tushar and Scharping, Nicole E and Moreci, Rebecca S and Delgoffe, Greg M (2015) Metabolic insufficiency underlies intratumoral cytotoxic T cell dysfunction. Journal for ImmunoTherapy of Cancer, 3 (Suppl ). P399 - P399. ISSN 2051-1426

Shayan, Gulidanna and Ferris, Robert L (2015) PD-1 blockade upregulate TIM-3 expression as a compensatory regulation of immune check point receptors in HNSCC TIL. Journal for ImmunoTherapy of Cancer, 3 (Suppl ). P196 - P196. ISSN 2051-1426

Ferris, Robert L and Kansy, Benjamin A and Gibson, Sandra and Srivastava, Raghvendra M and Bryan, James and Hershberg, Robert M (2015) A Phase Ib study of neoadjuvant immune biomarker modulation with cetuximab and motolimod in head and neck cancer (HNC). Journal for ImmunoTherapy of Cancer, 3 (Suppl ). P144 - P144. ISSN 2051-1426

Najjar, Yana G and Rayman, Patricia A and Tannenbaum, Charlie and Jia, Xuefei and Elson, Paul and Diaz-Montero, C Marcela and Hamilton, Tom and Rini, Brian and Finke, James (2014) Accumulation of MDSC subsets in renal cell carcinoma correlates with grade and progression free survival, and is associated with intratumoral expression of IL-1β, IL-8 and CXCL5. Journal for ImmunoTherapy of Cancer, 2 (S3).

Vujanovic, Lazar and Stahl, Elizabeth and Butterfield, Lisa H (2014) Alpha fetoprotein directly induces a unique pro-inflammatory, IL-2 hyperresponsive phenotype in human natural killer cells. Journal for ImmunoTherapy of Cancer, 2 (S3).

Wang, Wenqian and Vernon, Philip and Li, Guanqiao and Sampath, Padmavathi and Stephen, Thorne and Liang, Xiaoyan and Lotze, Michael (2014) Depletion of high mobility group box 1(HMGB1) in dendritic cells (DCs) suppresses tumorigenesis and promotes viral clearance. Journal for ImmunoTherapy of Cancer, 2 (S3).

Li, Jing and Ferris, Robert L (2014) Differential expression of PD-1 and Tim-3 marks activation versus exhaustion status of T cells in the tumor microenvironment. Journal for ImmunoTherapy of Cancer, 2 (S3).

Concha-Benavente, Fernando and Ferris, Robert L (2014) IFNγ-induced PD-L1 expression is JAK2 but not JAK1 dependent and its inhibition enhances NK-cetuximab mediated ADCC of HNSCC cells. Journal for ImmunoTherapy of Cancer, 2 (S3).

Kohanbash, Gary and Straw, Erin and Ahn, Brian and Okada, Hideho (2014) ONO-AE3-208 inhibits myeloid derived suppressor cells and glioma growth. Journal for ImmunoTherapy of Cancer, 2 (S3).

Li, Jing and Ferris, Robert L (2014) PD-1/SHP-2 negatively regulate Tc1/Th1 phenotypic responses and activation of T cells in the tumor microenvironment. Journal for ImmunoTherapy of Cancer, 2 (S3).

Hodi, F Stephen and Ribas, Antoni and Daud, Adil and Hamid, Omid and Robert, Caroline and Kefford, Richard and Hwu, Wen-Jen and Gangadhar, Tara C and Joshua, Anthony M and Hersey, Peter and Weber, Jeffrey and Joseph, Richard W and Zarour, Hassane and Dronca, Roxana and Gammage, Linda and Hille, Darcy and Xue, Dahai and Kang, S Peter and Chun, Patrick and Ebbinghaus, Scot W and Perrone, Andrea and Wolchok, Jedd D (2014) Patterns of response in patients with advanced melanoma treated with Pembrolizumab (MK-3475) and evaluation of immune-related response criteria (irRC). Journal for ImmunoTherapy of Cancer, 2 (S3).

Patricia, Santos and Alexander, Etheridge and Gambotto, Andrea and Butterfield, Lisa H (2014) Transduction of human dendritic cells with adenovirus encoding anti-PD-1 reduces PD-1 expression on co-cultured T cells. Journal for ImmunoTherapy of Cancer, 2 (S3).

Dutcher, JP and Schwartzentruber, DJ and Kaufman, HL and Agarwala, SS and Tarhini, AA and Lowder, JN and Atkins, MB (2014) High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014. Journal for ImmunoTherapy of Cancer, 2 (1).

Ferris, Robert L and Cohen, Ezra and Gash, Kelly and Whiting, Sam and Manjarrez, Kristi and Dietsch, Greg and Hershberg, Robert and Bryan, James (2014) Active8: a randomized, double-blind, placebo-controlled study of chemotherapy plus cetuximab in combination with TLR8 agonist VTX-2337 in patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN). Journal for ImmunoTherapy of Cancer, 2 (Suppl ). P69 - P69. ISSN 2051-1426

Wang-Gillam, Andrea and Picozzi, Vincent and Crocenzi, Todd and Morse, Michael and Zeh, Herbert and Fine, Robert and Murphy, Aimee and Skoble, Justin and Lemmens, Edward and Ferber, Sandy and Rosen, Allan and Grous, John and Dubensky, Thomas W and Brockstedt, Dirk and Jaffee, Elizabeth and Le, Dung (2014) A Phase IIb, randomized, multicenter study of the efficacy of GVAX pancreas vaccine and CRS-207 compared to chemotherapy or to CRS-207 alone in adults with previously-treated metastatic pancreatic adenocarcinoma (eclipse study). Journal for ImmunoTherapy of Cancer, 2 (Suppl ). P68 - P68. ISSN 2051-1426

Ohkuri, Takayuki and Ghosh, Arundhati and Kosaka, Akemi and Zhu, Jianzhong and Ikeura, Maki and David, Michael and Watkins, Simon C and Sarkar, Saumendra N and Okada, Hideho (2014) STING contributes to anti-glioma immunity via triggering type-I IFN signals in the tumor microenvironment. Journal for ImmunoTherapy of Cancer, 2 (Suppl ). P228 - P228. ISSN 2051-1426

Obermajer, Natasa and Wong, Jeffrey L and Edwards, Robert P and Chen, Kong and Scott, Melanie and Khader, Shabaana and Kolls, Jay K and Odunsi, Kunle and Billiar, Timothy R and Kalinski, Pawel (2013) Development and stability of Th17 cells in ovarian cancer requires nitric oxide and endogenous NOS2 activity in cancer-associated CD4+ T cells. Journal for ImmunoTherapy of Cancer, 1 (S1).

Wong, Jeffrey L and Muthuswamy, Ravikumar and Bartlett, David L and Kalinski, Pawel (2013) IL-18-based combinatorial adjuvants promote the NK-DC-mediated production of the CCR7 ligand CCL19 in lymph nodes from cancer patients. Journal for ImmunoTherapy of Cancer, 1 (S1).

Okada, Hideho and Butterfield, Lisa H and Hamilton, Ronald L and Salazar, Andres M and Potter, Douglas M and Lieberman, Frank S and Pollack, Ian F (2013) Promise and challenges of peptide-poly: ICLC vaccines for adult and pediatric gliomas. Journal for ImmunoTherapy of Cancer, 1 (S1).

Srivastava, Raghvendra M and Jie, Hyun-bae and Ferrone, Soldano and Ferris, Robert L (2013) STAT1 contributes to HLA class I upregulation and CTL reactivity after anti-EGFR mAb cetuximab therapy in head and neck cancer patients. Journal for ImmunoTherapy of Cancer, 1 (S1).

Muthuswamy, Ravikumar and Jenkins, Frank and Bovbjerg, Dana and Kalinski, Pawel (2013) Synergistic induction of cancer-related immunosuppression by β2-adrenergic stress mediators and P38MAPK inflammatory pathway. Journal for ImmunoTherapy of Cancer, 1 (S1).

Jie, Hyun-Bae and Li, Jing and Srivastava, Raghvendra and Ferris, Robert L (2013) TIM-3+ T cells are not exhausted but activated cells in the tumor microenvironment. Journal for ImmunoTherapy of Cancer, 1 (S1).

Naveh, HP and Vujanovic, L and Butterfield, LH (2013) Cellular immunity induced by a recombinant adenovirus-human dendritic cell vaccine for melanoma. Journal for ImmunoTherapy of Cancer, 1.

Stroncek, DF and Melief, CJM and Castiello, L and Cesano, A and Cheever, MA and Civini, S and Comin-Anduix, B and Gajewski, TF and Greenberg, PD and Kalinski, P and Kaufman, HL and Kershaw, MH and Khleif, SN and Marincola, F and Merritt, W and Munn, DH and Powell, DJ and Restifo, NP and Rosenberg, SA and Puri, RK and Streicher, H and Szalay, AA and Yee, C and Zitvogel, L and Ribas, A (2013) Highlights of the society for immunotherapy of cancer (SITC) 27th annual meeting. Journal for ImmunoTherapy of Cancer, 1.

Smith, Andressa A and Hodge, James and Garnett, Charlie and Farsaci, Benedetto and Palena, Claudia and Tsang, Kwong-Yok and Ferrone, Soldano and Gamiero, Sofia (2013) Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death. Journal for ImmunoTherapy of Cancer, 1 (Suppl ). P91 - P91. ISSN 2051-1426

Hong, Yuan and Peng, Yibing and Guo, Sheng Z and Pang, Junfeng and Guevara-patino, Jose and Munn, David H and Mivechi, Nahid and Bartlett, David and He, Yukai (2013) Epitope-optimization creates highly immunogenic alpha fetoprotein antigen to break immune tolerance and potently activates CD8 T cells to prevents autochthonous hepatocellular carcinoma. Journal for ImmunoTherapy of Cancer, 1 (Suppl ). P216 - P216. ISSN 2051-1426

Ohno, Masasuke and Ohkuri, Takayuki and Kosaka, Akemi and Tanahashi, Kuniaki and June, Carl H and Natsume, Atsushi and Okada, Hideho (2013) Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts. Journal for ImmunoTherapy of Cancer, 1 (1). 21 - 21. ISSN 2051-1426