Comprehensive analysis of preeclampsia-associated DNA methylation in the placenta

Chu, T and Bunce, K and Shaw, P and Shridhar, V and Althouse, A and Hubel, C and Peters, D (2014) Comprehensive analysis of preeclampsia-associated DNA methylation in the placenta. PLoS ONE, 9 (9).

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Abstract

Background:A small number of recent reports have suggested that altered placental DNA methylation may be associated with early onset preeclampsia. It is important that further studies be undertaken to confirm and develop these findings. We therefore undertook a systematic analysis of DNA methylation patterns in placental tissue from 24 women with preeclampsia and 24 with uncomplicated pregnancy outcome.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Chu, T tic19@pitt.edu TIC19 Bunce, K Shaw, P Shridhar, V Althouse, A Hubel, C hubelc@pitt.edu HUBELC Peters, D dgp6@pitt.edu DGP6
Contributors:	Contribution Contributors Name Email Pitt Username ORCID Editor Oudejans, Cees UNSPECIFIED UNSPECIFIED UNSPECIFIED
Centers:	Other Centers, Institutes, Offices, or Units > Magee-Women's Research Institute
Date:	23 September 2014
Date Type:	Publication
Journal or Publication Title:	PLoS ONE
Volume:	9
Number:	9
DOI or Unique Handle:	10.1371/journal.pone.0107318
Schools and Programs:	School of Medicine > Obstetrics, Gynecology, and Reproductive Sciences
Refereed:	Yes
Other ID:	NLM PMC4172433
PubMed Central ID:	PMC4172433
PubMed ID:	25247495
Date Deposited:	05 May 2015 16:37
Last Modified:	31 Mar 2021 12:55
URI:	http://d-scholarship.pitt.edu/id/eprint/24020

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