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Herpes simplex virus and varicella zoster virus, the house guests who never leave.

Kinchington, Paul R and Leger, Anthony J St and Guedon, Jean-Marc G and Hendricks, Robert L (2012) Herpes simplex virus and varicella zoster virus, the house guests who never leave. Herpesviridae, 3 (1). 5 - ?.

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Abstract

Human alphaherpesviruses including herpes simplex viruses (HSV-1, HSV-2) and varicella zoster virus (VZV) establish persistent latent infection in sensory neurons for the life of the host. All three viruses have the potential to reactivate causing recurrent disease. Regardless of the homology between the different virus strains, the three viruses are characterized by varying pathologies. This review will highlight the differences in infection pattern, immune response, and pathogenesis associated with HSV-1 and VZV.

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Kinchington, Paul Rkinch@pitt.eduKINCH
Leger, Anthony J St
Guedon, Jean-Marc G
Hendricks, Robert Lrlh13@pitt.eduRLH13
Date: 12 May 2012
Date Type: Acceptance
Journal or Publication Title: Herpesviridae
Volume: 3
Number: 1
Page Range: 5 - ?
DOI or Unique Handle: 10.1186/2042-4280-3-5
Schools and Programs: School of Medicine > Immunology
School of Medicine > Molecular Genetics and Developmental Biology
School of Medicine > Ophthalmology
Refereed: Yes
Funders: NEI NIH HHS (R01 EY005945), NEI NIH HHS (R01 EY015291), NINDS NIH HHS (R01 NS064022), NEI NIH HHS (T32 EY017271)
Date Deposited: 14 Oct 2016 15:41
Last Modified: 01 Nov 2017 14:06
URI: http://d-scholarship.pitt.edu/id/eprint/29878

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