The immunosuppressive effects of FR 900506 in rats receiving heterotopic cardiac allografts

Lee, P and Murase, N and Todo, S and Makowka, L and Starzl, T (1987) The immunosuppressive effects of FR 900506 in rats receiving heterotopic cardiac allografts. Surgical Research Communications, 1 (4). 325 - 331. ISSN 0882-9233

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Abstract

The immunosuppressive effects of FR 900506 were studied in Lewis rats given ACI heterotopic heart allografts. Intramuscular doses of 0.02 mg/kg daily for 2 weeks extended graft survival slightly, and with doses up to 1.28 mg/kg for 2 weeks, there is long-term survival. If only 3 daily doses were given starting on day 4 after transplantation, graft survival for almost 3 months was accomplished in 4 of 6 animals who still bear functioning hearts.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Lee, P Murase, N Todo, S Makowka, L Starzl, T tes11@pitt.edu TES11
Centers:	Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date:	1 January 1987
Date Type:	Publication
Journal or Publication Title:	Surgical Research Communications
Volume:	1
Number:	4
Page Range:	325 - 331
Institution:	University of Pittsburgh
Refereed:	Yes
ISSN:	0882-9233
Other ID:	uls-drl:31735062128644, Starzl CV No. 766
Date Deposited:	08 Apr 2010 17:13
Last Modified:	24 Jan 2019 00:55
URI:	http://d-scholarship.pitt.edu/id/eprint/4152

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