Starzl, TE and Van Thiel, D and Tzakis, AG and Iwatsuki, S and Todo, S and Marsh, JW and Koneru, B and Staschak, S and Stieber, A and Gordon, RD
(1988)
Orthotopic liver transplantation for alcoholic cirrhosis.
JAMA, 260 (17).
2542 - 2544.
ISSN 0098-7484
Abstract
Fifteen patients with Laennec's cirrhosis underwent orthotopic liver transplantation between 1963 and the end of 1979. The first eight patients died perioperatively or within two months, but four of the next seven patients had long survival; three are still alive after 11 to 14 years. After the introduction of cyclosporine therapy, 41 more patients with alcoholic cirrhosis were treated with liver transplantation from 1980 to June 1987. The one-year survival is 73.2%, and, after one to three years, 28 (68%) of the recipients are living. Of the 35 patients in the combined old and new series who lived for six months or longer, only two returned to alcohol abuse. Social and vocational rehabilitation has been the rule in these recipients who were selected primarily because of urgency of need, because they or their families insisted on treatment, and because they and their families thereby committed themselves to long-standing programs of alcoholism care.
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Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Starzl, TE | tes11@pitt.edu | TES11 | | Van Thiel, D | | | | Tzakis, AG | | | | Iwatsuki, S | | | | Todo, S | | | | Marsh, JW | | | | Koneru, B | | | | Staschak, S | | | | Stieber, A | | | | Gordon, RD | | | |
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Centers: |
Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute |
Date: |
4 November 1988 |
Date Type: |
Publication |
Journal or Publication Title: |
JAMA |
Volume: |
260 |
Number: |
17 |
Page Range: |
2542 - 2544 |
Institution: |
University of Pittsburgh |
Refereed: |
Yes |
Uncontrolled Keywords: |
Adult, Aged, Alcoholism, Cyclosporins, Ethics, Medical, Female, Follow-Up Studies, Humans, Liver Cirrhosis, Alcoholic, Liver Transplantation, Male, Middle Aged, Prognosis |
ISSN: |
0098-7484 |
Funders: |
NIDDK NIH HHS (R01 DK029961-19), NIADDK NIH HHS (AM 29961) |
Other ID: |
uls-drl:31735062130285, Starzl CV No. 878 |
Date Deposited: |
08 Apr 2010 17:15 |
Last Modified: |
13 Oct 2017 21:55 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/4264 |
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