Shapiro, R and Jordan, ML and Scantlebury, VP and Fung, JJ and Jensen, C and Vivas, C and McCauley, J and Irish, WD and Mitchell, S and Demetris, AJ
(1993)
Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report.
Transplant Proc, 25 (1 Pt 1).
669 - 672.
ISSN 0041-1345
Abstract
FK 506 was used as a primary immunosuppressive agent in 125 cases of renal transplantation in a randomized trial comparing FK 506/prednisone with FK 506/azathioprine/prednisone. With a mean follow-up of 5.5 +/- 2.5 months, there has been a 6-month actuarial patient survival of 99% and graft survival of 88%. There is no difference thus far between the two-drug and three-drug groups, although there may be less rejection and diabetes in the three-drug group. These results suggest that FK 506 is a useful immunosuppressive agent in kidney transplantation.
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Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Shapiro, R | | | | Jordan, ML | | | | Scantlebury, VP | | | | Fung, JJ | | | | Jensen, C | | | | Vivas, C | | | | McCauley, J | | | | Irish, WD | | | | Mitchell, S | | | | Demetris, AJ | | | |
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Centers: |
Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute |
Date: |
February 1993 |
Date Type: |
Publication |
Journal or Publication Title: |
Transplant Proc |
Volume: |
25 |
Number: |
1 Pt 1 |
Page Range: |
669 - 672 |
Institution: |
University of Pittsburgh |
Refereed: |
Yes |
Uncontrolled Keywords: |
Actuarial Analysis, Adult, Azathioprine, Drug Therapy, Combination, Follow-Up Studies, Graft Rejection, Graft Survival, Humans, Kidney Function Tests, Kidney Transplantation, Prednisone, Survival Analysis, Tacrolimus |
ISSN: |
0041-1345 |
Funders: |
NIDDK NIH HHS (R01 DK029961-19) |
Other ID: |
uls-drl:31735062112473, Starzl CV No. 1456 |
Date Deposited: |
08 Apr 2010 17:24 |
Last Modified: |
13 Oct 2017 22:55 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/4842 |
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