Starzl, TE and Demetris, AJ and Murase, N and Trucco, M and Thomson, AW and Rao, AS
(1995)
The changing immunology of organ transplantation.
Hospital Practice, 30 (10).
31 - 42.
ISSN 8750-2836
Abstract
The engrafted organ becomes a chimera as the recipient's leukocytes station themselves in the transplant. Remarkably, the recipient becomes chimeric as well, in a reverse migration involving immune cells from the graft. Interactions between donor and recipient cells are tolerogenic-a process with implications for the goal of graft acceptance with minimal immunosuppression.
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