Wilson, Stephen Jeffrey
(2005)
PUTTING CRAVING INTO CONTEXT: EFFECTS OF PERCEIVED SMOKING OPPORTUNITY ON THE NEURAL RESPONSE TO CIGARETTE CUE EXPOSURE.
Master's Thesis, University of Pittsburgh.
(Unpublished)
Abstract
Recent years have seen the emergence of research applying functional neuroimaging to the study of cue-elicited drug craving. This research has begun to identify a distributed system of brain activity during drug craving. Functional magnetic resonance imaging (fMRI) was used to examine the effects of smoking expectancy on the neural response to neutral (e.g., roll of tape) and smoking-related (holding a cigarette) stimuli in male cigarette smokers deprived of nicotine for 8 hours. As predicted, several brain regions exhibited differential activation during cigarette versus neutral cue exposure. Moreover, instructions about smoking opportunity affected cue-elicited activation in several regions. These results highlight the importance of perceived drug availability in the neurobiological response to drug cues.
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Details
Item Type: |
University of Pittsburgh ETD
|
Status: |
Unpublished |
Creators/Authors: |
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ETD Committee: |
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Date: |
3 February 2005 |
Date Type: |
Completion |
Defense Date: |
22 June 2004 |
Approval Date: |
3 February 2005 |
Submission Date: |
10 November 2004 |
Access Restriction: |
No restriction; Release the ETD for access worldwide immediately. |
Institution: |
University of Pittsburgh |
Schools and Programs: |
Dietrich School of Arts and Sciences > Psychology |
Degree: |
MS - Master of Science |
Thesis Type: |
Master's Thesis |
Refereed: |
Yes |
Uncontrolled Keywords: |
cue reactivity; drug craving; prefrontal cortex; drug cue; neuroimaging |
Other ID: |
http://etd.library.pitt.edu/ETD/available/etd-11102004-104431/, etd-11102004-104431 |
Date Deposited: |
10 Nov 2011 20:04 |
Last Modified: |
15 Nov 2016 13:51 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/9615 |
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