ETD

Exploring the Role of GDF15 in Diet-Induced Metabolic Dysfunction

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Title
  • Exploring the Role of GDF15 in Diet-Induced Metabolic Dysfunction
Date modified
  • 04/02/2026
Creator
Abstract
  • Obesity is a major driver of diet-induced metabolic dysfunction worldwide and underlies rising rates of metabolic syndrome, type 2 diabetes (T2D), and metabolic dysfunction–associated steatotic liver disease (MASLD). This global epidemic continues to accelerate, with projections estimating that by 2050 nearly 3.8 billion adults, representing mor...
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Degree discipline
  • Human Genetics
Degree grantor
  • University of Pittsburgh School of Public Health
Degree level
  • doctoral
Degree name
  • Doctor of Philosophy
Department
  • University of Pittsburgh School of Public Health
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MLA citation style (9th ed.)

Jake Kastroll. Exploring the Role of Gdf15 In Diet-induced Metabolic Dysfunction. d-scholarship.pitt.edu/concern/etds/e8b79e41-9b75-4274-a9e7-dfecf7118273.

APA citation style (7th ed.)

J. Kastroll. Exploring the Role of GDF15 in Diet-Induced Metabolic Dysfunction. https://d-scholarship.pitt.edu/concern/etds/e8b79e41-9b75-4274-a9e7-dfecf7118273

Chicago citation style (CMOS 17, author-date)

Jake Kastroll. Exploring the Role of Gdf15 In Diet-Induced Metabolic Dysfunction. https://d-scholarship.pitt.edu/concern/etds/e8b79e41-9b75-4274-a9e7-dfecf7118273.

Note: These citations are programmatically generated and may be incomplete.

In Collection:
Thumbnail Title Date Uploaded Visibility Actions
Kastroll_PhD_Dissertation_2026.pdf Kastroll_PhD_Dissertation_2026.pdf 2026-04-02 Public Download
Appendix_A.2.1_ANCOVA-Adjusted_Energy_Expenditure_by_Age__12_vs._52_Weeks___PDF__66_KB__2026.pdf Appendix_A.2.1_ANCOVA-Adjusted_Energy_Expenditure_by_Age__12_vs._52_Weeks___PDF__66_KB__2026.pdf 2026-04-02 Public Download
Appendix_A.2.2_Mini_Mouse_Universal_Genotyping_Array_Background_Confirmation__PDF__1_MB__2026.pdf Appendix_A.2.2_Mini_Mouse_Universal_Genotyping_Array_Background_Confirmation__PDF__1_MB__2026.pdf 2026-04-02 Public Download
Appendix_A.2.3_ANCOVA-Adjusted_Energy_Expenditure_by_Genotype__WT_vs._GDF15_KO___PDF__447_KB__2026.pdf Appendix_A.2.3_ANCOVA-Adjusted_Energy_Expenditure_by_Genotype__WT_vs._GDF15_KO___PDF__447_KB__2026.pdf 2026-04-02 Public Download
Appendix_A.2.4_GSEA_of_a_Murine_Ortholog_MASH_Progression_Signature_Across_Genotypes__PDF__326_KB__2026.pdf Appendix_A.2.4_GSEA_of_a_Murine_Ortholog_MASH_Progression_Signature_Across_Genotypes__PDF__326_KB__2026.pdf 2026-04-02 Public Download