Huang, Hanrui
(2013)
Characterization of anterior cerebral artery blood flow in resting state by using transcranial Doppler.
Master's Thesis, University of Pittsburgh.
(Unpublished)
This is the latest version of this item.
Abstract
Transcranial Doppler (TCD) recordings are used to monitor cerebral blood flow in main cerebral arteries. The resting state is usually characterized by using the mean velocity or the maximum Doppler shift frequency (an envelope signal) by insonating the middle cerebral arteries (MCAs). In this study, we characterized the cerebral blood flow in the anterior cerebral arteries (ACAs). We analyzed both the envelope signals and the raw signals obtained from bilateral insonation. We recruited 20 healthy subjects and conducted the data acquisition for 15 minutes. Features were extracted from the time domain, the frequency domain and the time-frequency domain. The results showed that gender-based statistical difference exists in the frequency domain and the time-frequency domain. However, no handedness effect was found. In the time domain, the information-theoretic features showed that the mutual dependence is higher in raw signals than in envelope signals. Finally, we concluded that insonating the ACA will serve as a complement of the MCA studies. Additionally, the investigation of the raw signals provided us with additional information that is not otherwise available from the envelope signals. The direct TCD raw-data utilization is therefore validated as a valuable resting-state characterization method.
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Details
Item Type: |
University of Pittsburgh ETD
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Status: |
Unpublished |
Creators/Authors: |
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ETD Committee: |
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Date: |
27 June 2013 |
Date Type: |
Publication |
Defense Date: |
25 March 2013 |
Approval Date: |
27 June 2013 |
Submission Date: |
26 March 2013 |
Access Restriction: |
No restriction; Release the ETD for access worldwide immediately. |
Number of Pages: |
58 |
Institution: |
University of Pittsburgh |
Schools and Programs: |
Swanson School of Engineering > Electrical Engineering |
Degree: |
MS - Master of Science |
Thesis Type: |
Master's Thesis |
Refereed: |
Yes |
Uncontrolled Keywords: |
Transcrannial Doppler, anterior cerebral artery, resting-state characteristics |
Date Deposited: |
27 Jun 2013 14:53 |
Last Modified: |
15 Nov 2016 14:10 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/17932 |
Available Versions of this Item
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Characterization of anterior cerebral artery blood flow in resting state by using transcranial Doppler. (deposited 27 Jun 2013 14:53)
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