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Improved response to face recognition in UHF fMRI through parallel transmission RF pulse design

Zheng, Hai and Zhao, Tiejun and Edelman, Kathryn and Qian, Yongxian and Ibrahim, Tamer S. and Aizenstein, Howard and Boada, Fernando E (2012) Improved response to face recognition in UHF fMRI through parallel transmission RF pulse design. In: 18th Annual Meeting of the Organization for Human Brain Mapping (OHBM) 2012, 10 June 2012 - 14 June 2012, Beijing, China.

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Abstract

The amygdala plays an important role in normal memory and attention, and is also identified as a key structure to understand disorders with emotions such as depression, autism, and schizophrenia. Ultra high magnetic field (UHF) MRI has been used to depict anatomical details in the brain that are not attainable at lower field strengths. Unfortunately, UHF fMRI is problematic due to large magnetic susceptibiity-induced (SI) artifacts. This SI artifact manifests signal loss near important functional regions, such as the amygdala and limits the reliability of UHF fMRI studies in this region due to the coupling between the artifact level and the subject's underlying anatomy. People have proposed to restore the SI signal loss, but Radio frequency (RF) pulse durations are impractically long. In this study, we demonstrate a whole-brain, practical and robust RF pulse design to reliably recover the fMRI signal from the amygdala at ultra high field. We have successfully demonstrated that PTX 3DTRF design can be used for improving the fMRI signal response in amygdala. This is the first time that whole-brain, tailored RF methodology in conjunction with PTX RF has been demonstrated for this purpose. Overall, the proposed methodology was found to be robust across volunteers, especially when the 5-spoke trajectory was used.


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Details

Item Type: Conference or Workshop Item (Poster)
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Zheng, Hai
Zhao, Tiejun
Edelman, Kathrynedelmank@pitt.eduEDELMANK
Qian, Yongxian
Ibrahim, Tamer S.
Aizenstein, Howardaizen@pitt.eduAIZEN
Boada, Fernando E
Date: 14 June 2012
Date Type: Publication
Journal or Publication Title: F1000 Research
Publisher: F1000 Research Ltd.
Event Title: 18th Annual Meeting of the Organization for Human Brain Mapping (OHBM) 2012
Event Dates: 10 June 2012 - 14 June 2012
Event Type: Conference
Schools and Programs: School of Medicine > Neurological Surgery
School of Medicine > Psychiatry
Swanson School of Engineering > Bioengineering
Refereed: No
ISSN: 2046-1402
Additional Information: Competing Interests: No competing interests were disclosed
Date Deposited: 29 Nov 2016 16:55
Last Modified: 01 Nov 2017 14:06
URI: http://d-scholarship.pitt.edu/id/eprint/30136

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