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Finite element modeling of human artery tissue with a nonlinear multi-mechanism inelastic material

Sidorov, Sergey A (2007) Finite element modeling of human artery tissue with a nonlinear multi-mechanism inelastic material. Doctoral Dissertation, University of Pittsburgh. (Unpublished)

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Due to limited experimental data and a lack of understanding of the underlying microstructural deformation mechanisms involved, modeling of material behavior of biomechanical tissues presents a rather formidable task. In this dissertation, a nonlinear multi-mechanism inelastic material model is introduced for modeling vascular tissue, collagen recruitment and elastin degradation. The model is implemented into the commercial finite element software package ANSYS with user programmable features. Although the idea of using several deformation mechanisms in the same material model is by no means novel, it is the first time such model is being implemented in a commercial finite element package and applied to a numerical study of physiological processes taking place inside the vascular walls. Two numerical examples are presented: a simulation of angioplasty procedure, and a finite element analysis of fusiform aneurysm development and growth. This is by far not the exhaustive list of possible applications of the developed material model; implementation in a commercial finite element code will help facilitate innovative developments, including new ways to surgically treat vascular disorders.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Sidorov, Sergey Asas73@pitt.eduSAS73
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairLovell,
Committee CoChairMarangoni, Roymaran@engr.pitt.eduMARAN
Committee MemberRobertson, Anneannerob@engr.pitt.eduRBERTSON
Committee MemberSlaughter, Williamwss@engr.pitt.eduWSS
Date: 18 June 2007
Date Type: Completion
Defense Date: 15 March 2007
Approval Date: 18 June 2007
Submission Date: 22 March 2007
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Institution: University of Pittsburgh
Schools and Programs: Swanson School of Engineering > Mechanical Engineering
Degree: PhD - Doctor of Philosophy
Thesis Type: Doctoral Dissertation
Refereed: Yes
Uncontrolled Keywords: ANSYS; FEA; finite element analysis; hyperelasticity; material modeling; soft tissue
Other ID:, etd-03222007-172059
Date Deposited: 10 Nov 2011 19:32
Last Modified: 15 Nov 2016 13:37


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