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Transplantation of the liver for metastatic endocrine tumors of the intestine and pancreas

Makowka, L and Tzakis, AG and Mazzaferro, V and Teperman, L and Demetris, AJ and Iwatsuki, S and Starzl, TE (1989) Transplantation of the liver for metastatic endocrine tumors of the intestine and pancreas. Surgery Gynecology and Obstetrics, 168 (2). 107 - 111. ISSN 0039-6087

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Abstract

In the Pittsburgh series of 1,000 orthotopic liver transplants (OLTx), from January 1981 to July 1987, the indication for transplantation in five patients consisted of unresectable hepatic metastases arising from endocrine tumors of gastrointestinal origin: glucagonoma, two patients; carcinoid, two, and gastrinoma, one patient. Three patients underwent resection of the primary tumor (two distal pancreatectomies and one ileal resection) at the time of the hepatic transplantation. All patients underwent extensive nodal dissection. Three of the five patients are alive with no evidence of residual disease after a median follow-up study of 12 months. Hepatic transplantation broadens the concept of radical excision of tumor and may be considered as a potential therapeutic approach for some highly selected instances of unresectable hepatic metastases arising from endocrine tumors of the intestine and pancreas.

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Makowka, L
Tzakis, AG
Mazzaferro, V
Teperman, L
Demetris, AJ
Iwatsuki, S
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1989
Date Type: Publication
Journal or Publication Title: Surgery Gynecology and Obstetrics
Volume: 168
Number: 2
Page Range: 107 - 111
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0039-6087
Other ID: uls-drl:31735062130798, Starzl CV No. 929
Date Deposited: 08 Apr 2010 17:15
Last Modified: 27 Jan 2019 02:55
URI: http://d-scholarship.pitt.edu/id/eprint/4315

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