Tzakis, AG and Cooper, MH and Dummer, JS and Ragni, M and Ward, JW and Starzl, TE
(1990)
Transplantation in HIV<sup>+</sup> patients.
Transplantation, 49 (2).
354 - 358.
ISSN 0041-1337
Abstract
Twenty-five whole-organ recipients treated from 1981 through September 1988 were HIV carriers. Eleven were infected before transplantation, although this was not known until later in 8 recipients. The other 14 were infected perioperatively. Ten of the 25 recipients were infants or children. The organs transplanted were the liver (n = 15), and the heart or kidney (n = 5, each). After a mean follow-up of 2.75 years (range, 0.7- 6.6 years), 13 recipients are alive. Survival is 7/15, 2/ 5, and 4/5 of the liver, heart, and kidney recipients, respectively. The best results were in the pediatric group (70% survival) in which only 1 of 10 patients died of AIDS. In contrast, AIDS caused the death of 5 of 15 adult recipients and was the leading cause of death. Transplantation plus immunosuppression appeared to shorten the AIDS-free time in HIV+ patients as compared to nontransplant hemophiliac and transfusion control groups. Accrual of HIV+ transplant recipients has slowed markedly since the systematic screening of donors, recipients, and blood products was begun in 1985. © 1990 by Williams & Wilkins.
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Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Tzakis, AG | | | | Cooper, MH | | | | Dummer, JS | | | | Ragni, M | | | | Ward, JW | | | | Starzl, TE | tes11@pitt.edu | TES11 | |
|
Centers: |
Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute |
Date: |
1 January 1990 |
Date Type: |
Publication |
Journal or Publication Title: |
Transplantation |
Volume: |
49 |
Number: |
2 |
Page Range: |
354 - 358 |
DOI or Unique Handle: |
10.1097/00007890-199002000-00025 |
Institution: |
University of Pittsburgh |
Refereed: |
Yes |
ISSN: |
0041-1337 |
Other ID: |
uls-drl:31735062110923, Starzl CV No. 1050 |
Date Deposited: |
08 Apr 2010 17:18 |
Last Modified: |
22 Jun 2021 14:56 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/4436 |
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