Browse by Publication

Lin, PL and Maiello, P and Gideon, HP and Coleman, MT and Cadena, AM and Rodgers, MA and Gregg, R and O’Malley, M and Tomko, J and Fillmore, D and Frye, LJ and Rutledge, T and DiFazio, RM and Janssen, C and Klein, E and Andersen, PL and Fortune, SM and Flynn, JAL (2016) PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis. PLoS Pathogens, 12 (7). ISSN 1553-7366

Buck, CB and Van Doorslaer, K and Peretti, A and Geoghegan, EM and Tisza, MJ and An, P and Katz, JP and Pipas, JM and McBride, AA and Camus, AC and McDermott, AJ and Dill, JA and Delwart, E and Ng, TFF and Farkas, K and Austin, C and Kraberger, S and Davison, W and Pastrana, DV and Varsani, A (2016) The Ancient Evolutionary History of Polyomaviruses. PLoS Pathogens, 12 (4). ISSN 1553-7366

Pandrea, I and Xu, C and Stock, JL and Frank, DN and Ma, D and Policicchio, BB and He, T and Kristoff, J and Cornell, E and Haret-Richter, GS and Trichel, A and Ribeiro, RM and Tracy, R and Wilson, C and Landay, AL and Apetrei, C (2016) Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques. PLoS Pathogens, 12 (1). ISSN 1553-7366

Schreiber, CA and Sakuma, T and Izumiya, Y and Holditch, SJ and Hickey, RD and Bressin, RK and Basu, U and Koide, K and Asokan, A and Ikeda, Y (2015) An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses. PLoS Pathogens, 11 (8). ISSN 1553-7366

Markus, A and Lebenthal-Loinger, I and Yang, IH and Kinchington, PR and Goldstein, RS (2015) An In Vitro Model of Latency and Reactivation of Varicella Zoster Virus in Human Stem Cell-Derived Neurons. PLoS Pathogens, 11 (6). ISSN 1553-7366

Dembowski, JA and DeLuca, NA (2015) Selective Recruitment of Nuclear Factors to Productively Replicating Herpes Simplex Virus Genomes. PLoS Pathogens, 11 (5). ISSN 1553-7366

Lennemann, NJ and Coyne, CB (2015) Catch Me If You Can: The Link between Autophagy and Viruses. PLoS Pathogens, 11 (3). 1 - 6. ISSN 1553-7366

Shu, Q and Lennemann, NJ and Sarkar, SN and Sadovsky, Y and Coyne, CB (2015) ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry. PLoS Pathogens, 11 (9). ISSN 1553-7366

Jhingran, A and Kasahara, S and Shepardson, KM and Junecko, BAF and Heung, LJ and Kumasaka, DK and Knoblaugh, SE and Lin, X and Kazmierczak, BI and Reinhart, TA and Cramer, RA and Hohl, TM (2015) Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection. PLoS Pathogens, 11 (1). 1 - 22. ISSN 1553-7366

Cox, RG and Mainou, BA and Johnson, M and Hastings, AK and Schuster, JE and Dermody, TS and Williams, JV (2015) Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes. PLoS Pathogens, 11 (12). ISSN 1553-7366

Hu, M and Wang, C and Li, W and Lu, W and Bai, Z and Qin, D and Yan, Q and Zhu, J and Krueger, BJ and Renne, R and Gao, SJ and Lu, C (2015) A KSHV microRNA Directly Targets G Protein-Coupled Receptor Kinase 2 to Promote the Migration and Invasion of Endothelial Cells by Inducing CXCR2 and Activating AKT Signaling. PLoS Pathogens, 11 (9). ISSN 1553-7366

Craigo, JK and Ezzelarab, C and Cook, SJ and Liu, C and Horohov, D and Issel, CJ and Montelaro, RC (2015) Protective Efficacy of Centralized and Polyvalent Envelope Immunogens in an Attenuated Equine Lentivirus Vaccine. PLoS Pathogens, 11 (1). 1 - 14. ISSN 1553-7366

Gideon, HP and Phuah, JY and Myers, AJ and Bryson, BD and Rodgers, MA and Coleman, MT and Maiello, P and Rutledge, T and Marino, S and Fortune, SM and Kirschner, DE and Lin, PL and Flynn, JAL (2015) Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization. PLoS Pathogens, 11 (1). 1 - 28. ISSN 1553-7366

Whibley, N and Gaffen, SL (2014) Brothers in Arms: Th17 and Treg Responses in Candida albicans Immunity. PLoS Pathogens, 10 (12). ISSN 1553-7366

Micci, L and Alvarez, X and Iriele, RI and Ortiz, AM and Ryan, ES and McGary, CS and Deleage, C and McAtee, BB and He, T and Apetrei, C and Easley, K and Pahwa, S and Collman, RG and Derdeyn, CA and Davenport, MP and Estes, JD and Silvestri, G and Lackner, AA and Paiardini, M (2014) CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells. PLoS Pathogens, 10 (10). ISSN 1553-7366

Wei, DG and Chiang, V and Fyne, E and Balakrishnan, M and Barnes, T and Graupe, M and Hesselgesser, J and Irrinki, A and Murry, JP and Stepan, G and Stray, KM and Tsai, A and Yu, H and Spindler, J and Kearney, M and Spina, CA and McMahon, D and Lalezari, J and Sloan, D and Mellors, J and Geleziunas, R and Cihlar, T (2014) Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing. PLoS Pathogens, 10 (4). ISSN 1553-7366

Kearney, MF and Spindler, J and Shao, W and Yu, S and Anderson, EM and O'Shea, A and Rehm, C and Poethke, C and Kovacs, N and Mellors, JW and Coffin, JM and Maldarelli, F (2014) Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy. PLoS Pathogens, 10 (3). ISSN 1553-7366

Hatfull, GF (2014) Mycobacteriophages: Windows into Tuberculosis. PLoS Pathogens, 10 (3). ISSN 1553-7366

Jones, M and Dry, IR and Frampton, D and Singh, M and Kanda, RK and Yee, MB and Kellam, P and Hollinshead, M and Kinchington, PR and O'Toole, EA and Breuer, J (2014) RNA-seq Analysis of Host and Viral Gene Expression Highlights Interaction between Varicella Zoster Virus and Keratinocyte Differentiation. PLoS Pathogens, 10 (1). ISSN 1553-7366

Gopal, R and Monin, L and Slight, S and Uche, U and Blanchard, E and A. Fallert Junecko, B and Ramos-Payan, R and Stallings, CL and Reinhart, TA and Kolls, JK and Kaushal, D and Nagarajan, U and Rangel-Moreno, J and Khader, SA (2014) Unexpected Role for IL-17 in Protective Immunity against Hypervirulent Mycobacterium tuberculosis HN878 Infection. PLoS Pathogens, 10 (5). ISSN 1553-7366

Kozakiewicz, L and Chen, Y and Xu, J and Porcelli, SA and Jacobs, WR and Chan, J and Wang, Y and Dunussi-Joannopoulos, K and Ou, Q and Flynn, JL (2013) B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response. PLoS Pathogens, 9 (7). ISSN 1553-7366

Kader, M and Smith, AP and Guiducci, C and Wonderlich, ER and Normolle, D and Watkins, SC and Barrat, FJ and Barratt-Boyes, SM (2013) Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection. PLoS Pathogens, 9 (7). ISSN 1553-7366

Fregoso, OI and Ahn, J and Wang, C and Mehrens, J and Skowronski, J and Emerman, M (2013) Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1. PLoS Pathogens, 9 (7). ISSN 1553-7366

Feliu, V and Vasseur, V and Grover, HS and Chu, HH and Brown, MJ and Wang, J and Boyle, JP and Robey, EA and Shastri, N and Blanchard, N (2013) Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite. PLoS Pathogens, 9 (6). ISSN 1553-7366

Josefsson, L and Palmer, S and Faria, NR and Lemey, P and Casazza, J and Ambrozak, D and Kearney, M and Shao, W and Kottilil, S and Sneller, M and Mellors, J and Coffin, JM and Maldarelli, F (2013) Single Cell Analysis of Lymph Node Tissue from HIV-1 Infected Patients Reveals that the Majority of CD4⁺ T-cells Contain One HIV-1 DNA Molecule. PLoS Pathogens, 9 (6). ISSN 1553-7366

Shingler, KL and Yoder, JL and Carnegie, MS and Ashley, RE and Makhov, AM and Conway, JF and Hafenstein, S (2013) The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating. PLoS Pathogens, 9 (3). ISSN 1553-7366

Tavis, JE and Cheng, X and Hu, Y and Totten, M and Cao, F and Michailidis, E and Aurora, R and Meyers, MJ and Jacobsen, EJ and Parniak, MA and Sarafianos, SG (2013) The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes. PLoS Pathogens, 9 (1). ISSN 1553-7366

Ma, D and Jasinska, A and Kristoff, J and Grobler, JP and Turner, T and Jung, Y and Schmitt, C and Raehtz, K and Feyertag, F and Martinez Sosa, N and Wijewardana, V and Burke, DS and Robertson, DL and Tracy, R and Pandrea, I and Freimer, N and Apetrei, C (2013) SIVagm Infection in Wild African Green Monkeys from South Africa: Epidemiology, Natural History, and Evolutionary Considerations. PLoS Pathogens, 9 (1). ISSN 1553-7366

Kerr, PJ and Ghedin, E and DePasse, JV and Fitch, A and Cattadori, IM and Hudson, PJ and Tscharke, DC and Read, AF and Holmes, EC (2012) Evolutionary History and Attenuation of Myxoma Virus on Two Continents. PLoS Pathogens, 8 (10). ISSN 1553-7366

Apetrei, C and Pandrea, I and Mellors, JW (2012) Nonhuman Primate Models for HIV Cure Research. PLoS Pathogens, 8 (8). ISSN 1553-7366

Meng, X and Zhao, G and Yufenyuy, E and Ke, D and Ning, J and DeLucia, M and Ahn, J and Gronenborn, AM and Aiken, C and Zhang, P (2012) Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid. PLoS Pathogens, 8 (8). ISSN 1553-7366

Pastrana, DV and Brennan, DC and Çuburu, N and Storch, GA and Viscidi, RP and Randhawa, PS and Buck, CB (2012) Neutralization serotyping of BK polyomavirus infection in kidney transplant recipients. PLoS Pathogens, 8 (4). ISSN 1553-7366

Achtman, M and Wain, J and Weill, FX and Nair, S and Zhou, Z and Sangal, V and Krauland, MG and Hale, JL and Harbottle, H and Uesbeck, A and Dougan, G and Harrison, LH and Brisse, S (2012) Multilocus sequence typing as a replacement for serotyping in Salmonella enterica. PLoS Pathogens, 8 (6). ISSN 1553-7366

Li, J and Sayeed, S and Robertson, S and Chen, J and McClane, BA (2011) Sialidases affect the host cell adherence and epsilon toxin-induced cytotoxicity of Clostridium perfringens type D strain CN3718. PLoS Pathogens, 7 (12). ISSN 1553-7366

Pandrea, I and Gaufin, T and Gautam, R and Kristoff, J and Mandell, D and Montefiori, D and Keele, BF and Ribeiro, RM and Veazey, RS and Apetrei, C (2011) Functional cure of sivagm infection in rhesus macaques results in complete recovery of CD4 ⁺T cells and is reverted by CD8 ⁺ cell depletion. PLoS Pathogens, 7 (8). ISSN 1553-7366

Zhao, G and Ke, D and Vu, T and Ahn, J and Shah, VB and Yang, R and Aiken, C and Charlton, LM and Gronenborn, AM and Zhang, P (2011) Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces. PLoS Pathogens, 7 (3). ISSN 1553-7366

Mukherjee, A and Morosky, SA and Delorme-Axford, E and Dybdahl-Sissoko, N and Oberste, MS and Wang, T and Coyne, CB (2011) The coxsackievirus B 3C^pro protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. PLoS Pathogens, 7 (3). ISSN 1553-7366

Wijewardana, V and Soloff, AC and Liu, X and Brown, KN and Barratt-Boyes, SM (2010) Early myeloid dendritic cell dysregulation is predictive of disease progression in simian immunodeficiency virus infection. PLoS Pathogens, 6 (12). ISSN 1553-7366

Bozym, RA and Morosky, SA and Kim, KS and Cherry, S and Coyne, CB (2010) Release of intracellular calcium stores facilitates coxsackievirus entry into polarized endothelial cells. PLoS Pathogens, 6 (10). ISSN 1553-7366

Riddick, NE and Hermann, EA and Loftin, LM and Elliott, ST and Wey, WC and Cervasi, B and Taaffe, J and Engram, JC and Li, B and Else, JG and Li, Y and Hahn, BH and Derdeyn, CA and Sodora, DL and Apetrei, C and Paiardini, M and Silvestri, G and Collman, RG (2010) A novel CCR5 mutation common in sooty mangabeys reveals sivsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo. PLoS Pathogens, 6 (8). 71 - 72. ISSN 1553-7366

Moser, Theresa S and Jones, Russell G and Thompson, Craig B and Coyne, Carolyn B and Cherry, Sara (2010) A Kinome RNAi Screen Identified AMPK as Promoting Poxvirus Entry through the Control of Actin Dynamics. PLoS Pathogens, 6 (6). e1000954 - e1000954.

Brian Mochon, A and Ye, J and Kayala, MA and Wingard, JR and Clancy, CJ and Hong Nguyen, M and Felgner, P and Baldi, P and Liu, H (2010) Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during Candidemia. PLoS Pathogens, 6 (3). ISSN 1553-7366

Pastrana, DV and Tolstov, YL and Becker, JC and Moore, PS and Chang, Y and Buck, CB (2009) Quantitation of human seroresponsiveness to Merkel cell polyomavirus. PLoS Pathogens, 5 (9). ISSN 1553-7366

Brown, KN and Wijewardana, V and Liu, X and Barratt-Boyes, SM (2009) Rapid influx and death of plasmacytoid dendritic cells in lymph nodes mediate depletion in acute simian immunodeficiency virus infection. PLoS Pathogens, 5 (5). ISSN 1553-7366

Lu, YJ and Gross, J and Bogaert, D and Finn, A and Bagrade, L and Zhang, Q and Kolls, JK and Srivastava, A and Lundgren, A and Forte, S and Thompson, CM and Harney, KF and Anderson, PW and Lipsitch, M and Malley, R (2008) Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathogens, 4 (9). ISSN 1553-7366

Nelson, MI and Edelman, L and Spiro, DJ and Boyne, AR and Bera, J and Halpin, R and Ghedin, E and Miller, MA and Simonsen, L and Viboud, C and Holmes, EC (2008) Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States. PLoS Pathogens, 4 (8). ISSN 1553-7366

Dugan, VG and Chen, R and Spiro, DJ and Sengamalay, N and Zaborsky, J and Ghedin, E and Nolting, J and Swayne, DE and Runstadler, JA and Happ, GM and Senne, DA and Wang, R and Slemons, RD and Holmes, EC and Taubenberger, JK (2008) The evolutionary genetics and emergence of avian influenza viruses in wild birds. PLoS Pathogens, 4 (5). ISSN 1553-7366

Li, J and McClane, BA (2008) A novel small acid soluble protein variant is important for spore resistance of most clostridium perfringens food poisoning isolates. PLoS Pathogens, 4 (5). ISSN 1553-7366

Nelson, MI and Viboud, C and Simonsen, L and Bennett, RT and Griesemer, SB and St. George, K and Taylor, J and Spiro, DJ and Sengamalay, NA and Ghedin, E and Taubenberger, JK and Holmes, EC (2008) Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918. PLoS Pathogens, 4 (2). ISSN 1553-7366

Maldarelli, F and Palmer, S and King, MS and Wiegand, A and Polis, MA and Mican, JA and Kovacs, JA and Davey, RT and Rock-Kress, D and Dewar, R and Liu, S and Metcalf, JA and Rehm, C and Brun, SC and Hanna, GJ and Kempf, DJ and Coffin, JM and Mellors, JW (2007) ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia. PLoS Pathogens, 3 (4). 484 - 488. ISSN 1553-7366

An, P and Li, HW and Hutcheson-Dilks, H and Nelson, G and Donfield, S and Goedert, JJ and Rinaldo, CR and Buchbinder, S and Kirk, GD and O'Brien, SJ and Winkler, CA (2007) Regulatory polymorphisms in the cyclophilin A gene, PPIA, accelerate progression to AIDS. PLoS Pathogens, 3 (6). 0849 - 0857. ISSN 1553-7366

Bringaud, F and Müller, M and Cerqueira, GC and Smith, M and Rochette, A and El-Sayed, NMA and Papadopoulou, B and Ghedin, E (2007) Members of a large retroposon family are determinants of post-transcriptional gene expression in Leishmania. PLoS Pathogens, 3 (9). 1291 - 1307. ISSN 1553-7366

Figueiredo, A and Moore, KL and Mak, J and Sluis-Cremer, N and De Bethune, MP and Tachedjian, G (2006) Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol. PLoS Pathogens, 2 (11). 1051 - 1059. ISSN 1553-7366

Rappocciolo, G and Piazza, P and Fuller, CL and Reinhart, TA and Watkins, SC and Rowe, DT and Jais, M and Gupta, P and Rinaldo, CR (2006) Erratum: DC-SIGN on B lymphocytes is required for transmission of HIV-1 to T lymphocytes (Plos Pathogens 2, 7 (3) DOI:10.1371/journal.ppat.0020070). PLoS Pathogens, 2 (8). 0808 - ?. ISSN 1553-7366

Steele, C and Rapaka, RR and Metz, A and Pop, SM and Williams, DL and Gordon, S and Kolls, JK and Brown, GD (2005) The beta-glucan receptor dectin-1 recognizes specific morphologies of aspergillus fumigatus. PLoS Pathogens, 1 (4). 0323 - 0334. ISSN 1553-7366