Esfandiari, Hamed and Loewen, Nils A. and Hassanpour, Kiana and Fatourechi, A and Yazdani, S and Yaseri, M and Pakravan, Mohammad
(2017)
Fuchs Heterochromic Iridocyclitis-Associated Glaucoma: A Retrospective Comparison of Primary Ahmed Glaucoma Valve implantation and Trabeculectomy with MMC.
(Submitted)
Abstract
Purpose: To compare the safety and efficacy of a primary trabeculectomy with mitomycin C (T) and an Ahmed glaucoma valve (AGV) implantation in patients with Fuchs heterochromic iridocyclitis (FHIC) related glaucoma, a rare complication of an uncommon form of uveitis.
Design: Retrospective comparative case series.
Method: Twenty-six patients with uncontrolled FHIC-associated glaucoma received T (n=12) or an AGV (n=14). Primary outcome measures were the surgical success defined as IOP ≤ 21 mmHg and decreased ≥ 20% from the baseline and no secondary glaucoma surgery. Secondary outcome measures were the number of glaucoma medications, complications, best corrected visual acuity (BCVA), and intraocular pressure.
Results: The follow-up (mean±SD) was 34.0±17.7 in T and 33.4±18.6 months in AGV (p = 0.837). The cumulative probability of success rate at the final follow-up at three years was 41.7% for T and 85.7% for AGV. There was no significant difference in complications between the two groups (P>0.05).
The mean preoperative IOP in T was 23.4±3.3 mmHg and 21.6±5.2 mmHg at the final visit (P= 0.041). In AGV, the preoperative IOP was 24±7.8 and 17.1±2.6 mmHg at the final visit (P= 0.003), respectively. AGV had a significantly lower average IOP at the final follow-up visit compared to T (P= 0.018).
The number of glaucoma medications at baseline was 3.3±0.5 in T and 3±0.6 in AGV (P= 0.233). This decreased significantly to 2.4±1.0 and 1.7±0.6 at the final follow-up (P= 0.008 and 0.002, respectively). Patients in AGV needed fewer glaucoma medications (P= 0.041). BCVA was equal in both groups and did not change (p>0.05).
Conclusion: Primary AGV had a higher success rate than T in the management of FHIC-associated glaucoma. The risk of cataract formation and progression was significantly higher following T in these patients.
Share
| Citation/Export: |
|
| Social Networking: |
|
Details
| Item Type: |
Article
|
| Status: |
Submitted |
| Creators/Authors: |
| Creators | Email | Pitt Username | ORCID  |
|---|
| Esfandiari, Hamed | | | | | Loewen, Nils A. | nal58@pitt.edu | NAL58 | | | Hassanpour, Kiana | | | | | Fatourechi, A | | | | | Yazdani, S | | | | | Yaseri, M | | | | | Pakravan, Mohammad | | | |
|
| Date: |
27 October 2017 |
| Schools and Programs: |
School of Medicine > Ophthalmology |
| Refereed: |
No |
| Article Type: |
Research Article |
| MeSH Headings: |
glaucoma; glaucoma surgery; tube shunt; trabeculectomy; Fuchs heterochromic iridocyclitis |
| Date Deposited: |
30 Oct 2017 15:07 |
| Last Modified: |
30 Oct 2017 15:07 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/33292 |
Metrics
Monthly Views for the past 3 years
Plum Analytics
Actions (login required)
 |
View Item |
![[feed]](/images/feed-icon-32x32.png){kind=icon}