Burckart, GJ and Ptachcinski, RJ and Jones, DH and Howrie, DL and Venkataramanan, R and Starzl, TE
(1987)
Impaired clearance of ceftizoxime and cefotaxime after orthotopic liver transplantation.
Antimicrob Agents Chemother, 31 (2).
323 - 324.
ISSN 0066-4804
Abstract
The pharmacokinetics of ceftizoxime (CZX) and of cefotaxime (CTX) were studied in five children and five adults after orthotopic liver transplantation (OLT). Delayed clearance of CZX (clearance of 0.21 to 1.26 ml/min per kg [body weight]) and CTX (clearance of 0.40 to 1.49 ml/min per kg) occurred in 7 of the 10 OLT patients. We conclude that abnormal CZX and CTX clearance is common after OLT and may be associated with minimal change in serum creatinine.
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Details
Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Burckart, GJ | | | | Ptachcinski, RJ | | | | Jones, DH | | | | Howrie, DL | | | | Venkataramanan, R | rv@pitt.edu | RV | | Starzl, TE | tes11@pitt.edu | TES11 | |
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Centers: |
Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute |
Date: |
February 1987 |
Date Type: |
Publication |
Journal or Publication Title: |
Antimicrob Agents Chemother |
Volume: |
31 |
Number: |
2 |
Page Range: |
323 - 324 |
DOI or Unique Handle: |
10.1128/aac.31.2.323 |
Institution: |
University of Pittsburgh |
Refereed: |
Yes |
Uncontrolled Keywords: |
Adult, Cefotaxime, Ceftizoxime, Child, Preschool, Humans, Infant, Kinetics, Liver Transplantation, Middle Aged, Regression Analysis |
ISSN: |
0066-4804 |
Other ID: |
uls-drl:31735062118967, Starzl CV No. 702 |
Date Deposited: |
08 Apr 2010 17:12 |
Last Modified: |
05 Jun 2021 10:55 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/4088 |
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